3-chloro-2-methoxy-5-(trifluoromethyl)pyridine

3-chloro-2-methoxy-5-(trifluoromethyl)pyridine - Names and Identifiers

Name	3-chloro-2-methoxy-5-(trifluoromethyl)pyridine
Synonyms	4-[(4-fluorobenzyl)oxy]-3-nitrobenzaldehyde 3-CHLORO-2-METHOXY-5-(TRIFLUOROMETHYL)PYRIDINE 3-chloro-5-(trifluoromethyl)-2-methoxypyridine 3-chloro-2-methoxy-5-(trifluoromethyl)ryridine 3-chloro-2-methoxy-5-(trifluoromethyl)pyridine Pyridine, 3-chloro-2-methoxy-5-(trifluoromethyl)-
CAS	175136-17-1
InChI	InChI=1/C14H10FNO4/c15-12-4-1-10(2-5-12)9-20-14-6-3-11(8-17)7-13(14)16(18)19/h1-8H,9H2

3-chloro-2-methoxy-5-(trifluoromethyl)pyridine - Physico-chemical Properties

Molecular Formula	C7H5ClF3NO
Molar Mass	211.57
Density	1.390±0.06 g/cm3(Predicted)
Boling Point	173 °C
Flash Point	223.4°C
Vapor Presure	3.82E-08mmHg at 25°C
pKa	-1.31±0.20(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.617

3-chloro-2-methoxy-5-(trifluoromethyl)pyridine - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R20/22 - Harmful by inhalation and if swallowed.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S23 - Do not breathe vapour.
Hazard Class	IRRITANT

3-chloro-2-methoxy-5-(trifluoromethyl)pyridine - Introduction

3-chloro-2-methoxy-5-(trifluoromethyl)pyridine is an organic compound with the chemical formula C10H6ClF3NO. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
1. Appearance: 3-chloro-2-methoxy-5-(trifluoromethyl)pyridine is a colorless to yellow crystal or powder substance.
2. Melting Point: about 57-59 ° C.
3. Solubility: It is soluble in most organic solvents, such as ethanol, dimethyl sulfoxide and dichloromethane.

Use:
1. 3-chloro-2-methoxy-5-(trifluoromethyl)pyridine is an important organic synthesis intermediate that can be used to prepare other compounds.
2. It can be used in the production of pesticides, herbicides and fungicides.

Method:
3-chloro-2-methoxy-5-(trifluoromethyl)pyridine can be synthesized by the following steps:
1. Synthesis of 2-amino -6-chloropyridine.
2. Reacting 2-amino -6-chloropyridine with methanol to give 2-amino -6-methoxypyridine.
3. 2-amino-6-methoxypyridine is reacted with trifluoromethylcupric chloride to obtain 3-chloro-2-methoxy-5-(trifluoromethyl)pyridine.

Safety Information:
1. 3-chloro-2-methoxy-5-(trifluoromethyl)pyridine is an organic synthesis intermediate, so it needs to be operated with caution and follow relevant safety measures.
2. It may cause harm to the environment, and attention should be paid to the treatment and disposal after medication.
3. During use, avoid contact with skin, eyes and respiratory tract, and prevent inhalation and ingestion.
4. In case of accidental contact or misuse, seek medical attention immediately and bring the container or label of the compound.
5. During use and storage, please keep it properly and keep it away from fire and storage temperature higher than room temperature.

Last Update：2024-04-10 22:29:15