3-fluoro-5-chloroaniline
3-Chloro-5-fluoroaniline
CAS: 4863-91-6
Molecular Formula: C6H5ClFN
3-fluoro-5-chloroaniline - Names and Identifiers
| Name | 3-Chloro-5-fluoroaniline |
| Synonyms | ZR CG EF BUTTPARK 44 1-96 3-Chloro-5-fluoroaniline 3-fluoro-5-chloroaniline 3-CHLORO-5-FLUOROANILINE 1-Amino-3-chloro-5-fluorobenzene |
| CAS | 4863-91-6 |
| InChI | InChI=1/C6H5ClFN/c7-4-1-5(8)3-6(9)2-4/h1-3H,9H2 |
3-fluoro-5-chloroaniline - Physico-chemical Properties
| Molecular Formula | C6H5ClFN |
| Molar Mass | 145.56 |
| Density | 1.45 |
| Boling Point | 98C/19Torr |
| Flash Point | 91.6°C |
| Vapor Presure | 0.0761mmHg at 25°C |
| Appearance | Liquid |
| Color | Clear light yellow to orange |
| pKa | 2.52±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.561-1.563 |
3-fluoro-5-chloroaniline - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R22 - Harmful if swallowed |
| Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 2810 |
| HS Code | 29214200 |
| Hazard Note | Toxic |
| Hazard Class | 6.1 |
3-fluoro-5-chloroaniline - Introduction
3-Chloro-5-fluoroaniline is an organic compound with the chemical formula C6H5ClFN. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: Colorless to light yellow solid
-Melting point: 43-47°C
-Boiling Point: 202-207°C
-Density: 1.393g/cm3
-Solubility: Slightly soluble in water, soluble in some organic solvents such as ethanol and ether
Use:
- 3-Chloro-5-fluoroaniline is an important organic synthesis intermediate, commonly used in the preparation of other compounds, such as fluorescent dyes, pharmaceuticals and pesticides.
-It is also commonly used to synthesize biologically active molecules in the field of drug development.
Preparation Method:
-3-oro-5-fluoraniline is generally prepared by taking 3-chloro-5-fluoronitrobenzene (chlorobenzene) as a starting compound, and then performing hydrogen reduction or reduction with ferrous iron.
-In the reaction, the nitro group will be reduced to an amino group to obtain 3-Chloro-5-fluoroaniline.
Safety Information:
- 3-Chloro-5-fluoroaniline is an organic compound, so pay attention to safe operation when using it.
-It is irritating and may cause irritation and damage to the skin, eyes, and respiratory tract when contacted. Direct contact should be avoided and appropriate personal protective equipment, such as gloves, protective glasses and protective face masks, should be worn during use.
-You should also pay attention to avoid inhaling its vapor, and avoid eating and entering the eyes by mistake. In case of contact, immediately flush the affected area with plenty of water and seek medical help.
-During storage and handling, fire and explosion prevention measures should be taken to avoid contact with oxidants and strong acids.
Nature:
-Appearance: Colorless to light yellow solid
-Melting point: 43-47°C
-Boiling Point: 202-207°C
-Density: 1.393g/cm3
-Solubility: Slightly soluble in water, soluble in some organic solvents such as ethanol and ether
Use:
- 3-Chloro-5-fluoroaniline is an important organic synthesis intermediate, commonly used in the preparation of other compounds, such as fluorescent dyes, pharmaceuticals and pesticides.
-It is also commonly used to synthesize biologically active molecules in the field of drug development.
Preparation Method:
-3-oro-5-fluoraniline is generally prepared by taking 3-chloro-5-fluoronitrobenzene (chlorobenzene) as a starting compound, and then performing hydrogen reduction or reduction with ferrous iron.
-In the reaction, the nitro group will be reduced to an amino group to obtain 3-Chloro-5-fluoroaniline.
Safety Information:
- 3-Chloro-5-fluoroaniline is an organic compound, so pay attention to safe operation when using it.
-It is irritating and may cause irritation and damage to the skin, eyes, and respiratory tract when contacted. Direct contact should be avoided and appropriate personal protective equipment, such as gloves, protective glasses and protective face masks, should be worn during use.
-You should also pay attention to avoid inhaling its vapor, and avoid eating and entering the eyes by mistake. In case of contact, immediately flush the affected area with plenty of water and seek medical help.
-During storage and handling, fire and explosion prevention measures should be taken to avoid contact with oxidants and strong acids.
Last Update：2024-04-09 15:17:58
