3-fluoro-pyridine-1-oxide - Names and Identifiers
3-fluoro-pyridine-1-oxide - Physico-chemical Properties
Molecular Formula | C5H4FNO
|
Molar Mass | 113.09 |
Density | 1.18 |
Melting Point | 65-68°C |
Boling Point | 275℃ |
Flash Point | 120℃ |
Water Solubility | Slightly soluble in water. |
Vapor Presure | 0.00892mmHg at 25°C |
pKa | 0.16±0.10(Predicted) |
Storage Condition | Room Temprature |
Refractive Index | 1.494 |
MDL | MFCD03095181 |
3-fluoro-pyridine-1-oxide - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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3-fluoro-pyridine-1-oxide - Introduction
3-Fluoropyridine N-oxide is an organic compound with the chemical formula C5H4FNO. It is a colorless liquid with a strong pungent odor. The following is a description of the nature, use, preparation and safety information of 3-Fluoropyridine N-oxide:
Nature:
-Appearance: colorless liquid
-Density: about 1.34 g/mL
-Melting point:-45 ℃
-Boiling point: 90 ℃
-Flash Point: 20 ℃
-Solubility: Soluble in polar organic solvents such as ethanol, ether and dichloromethane
Use:
- 3-Fluoropyridine N-oxide is an important organic synthesis intermediate, which can be used to synthesize other organic compounds and drugs.
-It can also be used as an oxidant to participate in some chemical reactions, such as oxyenols, thiols, etc.
Preparation Method:
3-Fluoropyridine N-oxide can be prepared by various methods, and the commonly used methods include:
-3-fluoropyridine reacts with benzoyl peroxide or tert-butyryl peroxide.
-It is prepared by further oxidation of 3-fluoropyridine.
Safety Information:
- 3-Fluoropyridine is N-oxide irritating and may be toxic. Use should pay attention to protective measures, such as wearing protective gloves, glasses and respirators.
-avoid contact with skin, eyes and other mucous membranes, if accidentally contact, immediately rinse with plenty of water, and seek medical help.
-During use and storage, keep away from fire and heat sources and avoid contact with flammable substances.
In general, 3-Fluoropyridine N-oxide is an important organic synthesis intermediate, which has a wide range of applications in the field of synthetic chemistry and medicine. But should pay attention to safe operation, follow the correct protective measures.
Last Update:2024-04-09 15:18:00