3-氟-4-羟基苯乙酸

3-氟-4-羟基苯乙酸 - Names and Identifiers

Name	3-Fluoro-4-hydroxyphenylacetic acid
Synonyms	4-(Carboxymethyl)-2-fluorophenol 3-Fluoro-4-HydroxyphenylaceticAci (3-fluoro-4-hydroxyphenyl)acetate 3-Fluoro-4-hydroxyphenylacetic acid 3-FLUORO-4-HYDROXYPHENYLACETIC ACID 3-Fluoro-4-hydroxybenzeneacetic acid 2-(3-fluoro-4-hydroxyphenyl)acetic acid Benzeneacetic acid, 3-fluoro-4-hydroxy- 4-(Carboxymethyl)-2-fluorophenol, (3-Fluoro-4-hydroxyphenyl)acetic acid
CAS	458-09-3
EINECS	207-275-8
InChI	InChI=1/C8H7FO3/c9-6-3-5(4-8(11)12)1-2-7(6)10/h1-3,10H,4H2,(H,11,12)/p-1

3-氟-4-羟基苯乙酸 - Physico-chemical Properties

Molecular Formula	C8H7FO3
Molar Mass	170.14
Density	1.423±0.06 g/cm3(Predicted)
Melting Point	132-134 °C (lit.)
Boling Point	320.3±27.0 °C(Predicted)
Flash Point	147.5°C
Vapor Presure	0.000133mmHg at 25°C
Appearance	Crystallization
Color	White to beige
pKa	4.30±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
MDL	MFCD00004348

3-氟-4-羟基苯乙酸 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	29182900
Hazard Class	IRRITANT

3-氟-4-羟基苯乙酸 - Introduction

Acid is an organic compound with the chemical formula C8H7FO3. It has a fluorine atom and a hydroxyl substituted phenylacetic acid structure.

This compound has the following properties:
-Appearance: White crystalline powder
-Melting point: about 150-152°C
-Solubility: Soluble in water and common organic solvents, such as alcohols and ethers

The acid can be used for a variety of purposes:
-Pharmaceutical field: As an important drug intermediate, it can be used to synthesize biologically active drug molecules.
-Agriculture: Can be used for research and development and production of pesticides and plant growth regulators.
-Chemical research field: It can be used as a substrate or starting material for organic synthesis reactions and participate in a variety of organic synthesis reactions.

One way to prepare the fluorobenzoic acid is to hydroxylate 3-fluorobenzoic acid with liquid ammonia, sodium hydroxide and cuprous hydroxide.

Regarding its safety information, the following points need to be noted:
-This compound may be irritating, and care should be taken to avoid skin contact and inhalation.
-When operating, please be equipped with appropriate personal protective equipment, such as gloves and safety glasses.
-During storage and handling, avoid contact with strong oxidants and strong acids to prevent possible dangerous reactions.

When using and handling this compound, please follow the relevant safety guidelines and regulations. If necessary, please operate under the guidance of experienced chemists.

Last Update：2024-04-09 19:05:49