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3-羟基-3-甲基谷氨酸

3-hydroxy-3-methylglutaric acid

CAS: 503-49-1

Molecular Formula: C6H10O5

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3-羟基-3-甲基谷氨酸 - Names and Identifiers

Name 3-hydroxy-3-methylglutaric acid
Synonyms hmga
Meglutol
lipoglutaren
medroglutaricacid
3-Hydroxymethylglutaric acid
3-hydroxy-3-methylglutaric acid
3-HYDROXY-3-METHYLPENTANEDIOIC ACID (HMG)
CAS 503-49-1
EINECS 207-971-1

3-羟基-3-甲基谷氨酸 - Physico-chemical Properties

Molecular FormulaC6H10O5
Molar Mass162.14
Density1.2132 (rough estimate)
Melting Point105-108 °C (lit.)
Boling Point120 °C / 13mmHg
pKa3.95±0.10(Predicted)
Storage Condition-20°C
Refractive Index1.4230 (estimate)
MDLMFCD00002712

3-羟基-3-甲基谷氨酸 - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany2
RTECSMA3753000
FLUKA BRAND F CODES10
HS Code29181990
ToxicityLD50 in mice (g/kg): 7.33 orally; 3.23 i.p. (Savoie, Lupien)

3-羟基-3-甲基谷氨酸 - Upstream Downstream Industry

Raw MaterialsEthyl acetate
Diethyl ether
Sulfuric acid
Tetrahydrofuran
Dichloromethane
Acetic acid
Sodium sulfate
Potassium hydroxide
Hydrogen peroxide
Magnesium
Allyl bromide
Downstream Products3-METHYLPENTANE-1,3,5-TRIOL
D(+)-Glucose

3-羟基-3-甲基谷氨酸 - Uses and synthesis methods

biological activity

Meglutol is an antilipemic agent that reduces cholesterol, triglycerides, and serum β-lipoproteins and phospholipids, and inhibits hydroxymethylglutaryl coenzyme A reductase activity, which is a rate-limiting enzyme in cholesterol biosynthesis.

Target

Human Endogenous Metabolite

Last Update:2024-04-09 01:59:50

3-羟基-3-甲基谷氨酸 - Nature

BRN 1769194
Last Update:2024-04-09 19:04:56
3-羟基-3-甲基谷氨酸
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Shanghai Macklin Biochemical Co., Ltd
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CAS: 503-49-1
Tel: 18301782025
Email: 3008007409@qq.com
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: 3-Hydroxy-3-methylglutaric Acid Visit Supplier Webpage Request for quotation
CAS: 503-49-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
MedChemExpress (MCE)
Spot supply
Product Name: Meglutol Visit Supplier Webpage Request for quotation
CAS: 503-49-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: 3-HYDROXY-3-METHYLGLUTARIC ACID Visit Supplier Webpage Request for quotation
CAS: 503-49-1
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Meglutol Visit Supplier Webpage Request for quotation
CAS: 503-49-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: 3-Hydroxy-3-Methylglutaric Acid Visit Supplier Webpage Request for quotation
CAS: 503-49-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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3-羟基-3-甲基谷氨酸
Raw Materials for 3-羟基-3-甲基谷氨酸
Sodium sulfate
Hydrogen peroxide
Magnesium
Allyl bromide
Downstream Products for 3-羟基-3-甲基谷氨酸
3-METHYLPENTANE-1,3,5-TRIOL
D(+)-Glucose
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