Molecular Formula | C10H14N2O |
Molar Mass | 178.23 |
Density | 1.077±0.06 g/cm3(Predicted) |
Melting Point | 147 °C |
Boling Point | 355.7±25.0 °C(Predicted) |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Appearance | neat |
Color | Off-White to Light Brown |
BRN | 2804946 |
pKa | 14.43±0.46(Predicted) |
Storage Condition | -20°C Freezer, Under inert atmosphere |
Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
Hazard Class | IRRITANT |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Overview | anthranilic acid isopropionamide can be used as a pharmaceutical synthesis intermediate, such as the preparation of melaxone. Melaxone is an important post-emergence herbicide with the chemical name 3-isopropyl-(1H)-benzo -2,1, 3-thiadiazin-4-one -2,2-dioxide, which was originally developed by the German BASF Company and is widely used in the world. It is a selective contact type herbicide, used for weed seedling stem and leaf treatment, the drug has strong contact, good selectivity, see grass and other characteristics, mainly used in rice, soybean, peanut, wheat and other crops, broad-leaved weeds and Cyperaceae weeds, grass weeds ineffective. |
Use | anthranilic acid isopropionamide can be used as a pharmaceutical synthesis intermediate, such as preparation of melaxone. |
preparation | preparation of isopropionamide anthranilate: isopropylamine was added dropwise by dissolving isatoic anhydride in dichloroethane while warming, after warming to 60 ° C, the temperature was maintained for 0.8h, and then the dichloroethane was removed by washing with saturated sodium carbonate to obtain light yellow O-amino-N-isopropylbenzamide solution, the mass ratio of dichloroethane to isopropylamine was 3.5:2.6:1.8. |