31373-65-6
N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine
CAS: 31373-65-6
Molecular Formula: C21H27N5O5
31373-65-6 - Names and Identifiers
| Name | N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine |
| Synonyms | Bz-Gly-His-Leu Hippuryl-His-Leu H-HIP-HIS-LEU-OH BZ-GLY-HIS-LEU-OH BENZOYL-GLY-HIS-LEU N-Benzoyl-Gly-L-His-L-Leu-OH HIPPURYL-L-HISTIDYL-L-LEUCINE Nα-(Benzoylglycyl)-L-His-L-Leu-OH N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine |
| CAS | 31373-65-6 |
| EINECS | 250-597-9 |
| InChI | InChI=1/C21H27N5O5/c1-13(2)8-17(21(30)31)26-20(29)16(9-15-10-22-12-24-15)25-18(27)11-23-19(28)14-6-4-3-5-7-14/h3-7,10,12-13,16-17H,8-9,11H2,1-2H3,(H,22,24)(H,23,28)(H,25,27)(H,26,29)(H,30,31)/p-1/t16-,17-/m0/s1 |
31373-65-6 - Physico-chemical Properties
| Molecular Formula | C21H27N5O5 |
| Molar Mass | 429.47 |
| Density | 1.283±0.06 g/cm3(Predicted) |
| Boling Point | 912.4±65.0 °C(Predicted) |
| Flash Point | 505.6°C |
| Solubility | acetic acid: 50mg/mL, clear, colorless |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | powder |
| Color | white to off-white |
| pKa | 3.26±0.10(Predicted) |
| Storage Condition | −20°C |
31373-65-6 - Risk and Safety
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
31373-65-6 - Reference
| Reference Show more | 1. Rongyali, Zhou, Tingting, Schwann, et al. Purification and characterization of carboxypeptidase from Antarctic krill [J]. Journal of Shanghai Ocean University 2020(4). 2. [IF = 7.514] Junbo Chen et al."Screening and mechanisms of novel angiotensin-I-converting in vitro study."Food Chem. 2022 Feb;370:131070 3. [IF=5.279] Yanbo Huang et al."Novel ACE Inhibitory Peptides Derived from Yeast Hydrolysates: Screening, Inhibition Mechanisms and Effects on HUVECs."J Agr Food Chem. 2021;69(8):2412-2421 |
31373-65-6 - Introduction
N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine is an organic compound with the formula N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine. The following is a description of the nature, use, preparation and safety information of N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine:
Nature:
-Appearance: N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine may be white or off-white crystalline powder.
-Solubility: The solubility in water is low and difficult to dissolve. It can be dissolved in organic solvents such as dimethyl sulfoxide (DMSO) and methanol.
Use:
-Biological activity Research: N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine are widely used in biological activity research and drug development.
-Metabolic pathway research: It can be used as a peptide fragment in the study of protein structure and function.
-Drug delivery carrier: N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine can be used as a drug delivery carrier for drug delivery to increase the stability and selectivity of drugs.
Method:
The preparation of N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine is usually carried out by solid phase synthesis. It is synthesized by sequentially attaching the appropriate amino acid residues to a polypeptide chain. Synthetic methods typically involve chemical protecting groups that protect the carboxyl and amino groups to prevent unwanted chemical reactions from occurring during the reaction.
Safety Information:
- N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine is considered to be a relatively safe substance under general conditions.
-Due to the lack of extensive toxicity and safety data, caution is required when using.
-Observe appropriate laboratory safety procedures and wear personal protective equipment, such as lab gloves and protective glasses.
-In the event of accidental exposure or ingestion of the substance, seek immediate medical assistance and provide appropriate chemical information.
Nature:
-Appearance: N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine may be white or off-white crystalline powder.
-Solubility: The solubility in water is low and difficult to dissolve. It can be dissolved in organic solvents such as dimethyl sulfoxide (DMSO) and methanol.
Use:
-Biological activity Research: N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine are widely used in biological activity research and drug development.
-Metabolic pathway research: It can be used as a peptide fragment in the study of protein structure and function.
-Drug delivery carrier: N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine can be used as a drug delivery carrier for drug delivery to increase the stability and selectivity of drugs.
Method:
The preparation of N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine is usually carried out by solid phase synthesis. It is synthesized by sequentially attaching the appropriate amino acid residues to a polypeptide chain. Synthetic methods typically involve chemical protecting groups that protect the carboxyl and amino groups to prevent unwanted chemical reactions from occurring during the reaction.
Safety Information:
- N-[N-(N-benzoylglycyl)-L-histidyl]-L-leucine is considered to be a relatively safe substance under general conditions.
-Due to the lack of extensive toxicity and safety data, caution is required when using.
-Observe appropriate laboratory safety procedures and wear personal protective equipment, such as lab gloves and protective glasses.
-In the event of accidental exposure or ingestion of the substance, seek immediate medical assistance and provide appropriate chemical information.
Last Update：2024-04-09 21:04:16
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Product Name: Hippuryl-His-Leu Visit Supplier Webpage Request for quotationCAS: 31373-65-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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