3163-07-3
4-Nitrobenzene-1,3-diol
CAS: 3163-07-3
Molecular Formula: C6H5NO4
3163-07-3 - Names and Identifiers
| Name | 4-Nitrobenzene-1,3-diol |
| Synonyms | Einecs 221-616-8 4-Nitroresorcinol 4-Nitrobenzene-1,3-diol |
| CAS | 3163-07-3 |
| EINECS | 221-616-8 |
3163-07-3 - Physico-chemical Properties
| Molecular Formula | C6H5NO4 |
| Molar Mass | 155.11 |
| Density | 1.5553 (rough estimate) |
| Melting Point | 122 °C |
| Boling Point | 278.88°C (rough estimate) |
| Water Solubility | 8.13g/L(24.70 ºC) |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | Yellow |
| pKa | 7.17±0.13(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Irritant |
| Refractive Index | 1.5423 (estimate) |
| MDL | MFCD04117945 |
3163-07-3 - Introduction
4-Nitrobenzene-1,3-diol is an organic compound with the chemical formula C6H5(NO2)(OH)2. The following is a description of its nature, use, preparation and safety information:
Nature:
- 4-Nitrobenzene-1,3-diol is a colorless crystalline solid that can be dissolved in water and organic solvents.
-It has phenoxy and nitro functional groups, so it has the characteristics of phenol and nitro compounds.
Use:
- 4-Nitrobenzene-1,3-diol is widely used in organic synthesis. Due to the existence of nitro and hydroxyl groups, it can be used as a reagent for alkylation, phenol-formaldehyde condensation, nucleophilic substitution and other reactions.
-It can also be used for the preparation of photochromic materials, dyes and fungicides.
Preparation Method:
- 4-Nitrobenzene-1,3-diol can be prepared by nitration of p-nitrophenol. First, nitrobenzene and concentrated sulfuric acid are mixed, heated to an appropriate temperature, and after a period of reaction, water is added to stop the reaction. After that, 4-Nitrobenzene-1,3-diol was obtained by crystallization purification.
Safety Information:
- 4-Nitrobenzene-1,3-diol is dangerous and should be handled with care.
-It may cause irritation or damage to the eyes, skin, respiratory and digestive systems.
-Wear appropriate protective equipment such as gloves, glasses and protective clothing during use or handling.
-Avoid inhaling its dust or contact with the skin.
-If inhaled or ingested by mistake, seek medical attention immediately and explain to your doctor with a label on the packaging or chemical.
Nature:
- 4-Nitrobenzene-1,3-diol is a colorless crystalline solid that can be dissolved in water and organic solvents.
-It has phenoxy and nitro functional groups, so it has the characteristics of phenol and nitro compounds.
Use:
- 4-Nitrobenzene-1,3-diol is widely used in organic synthesis. Due to the existence of nitro and hydroxyl groups, it can be used as a reagent for alkylation, phenol-formaldehyde condensation, nucleophilic substitution and other reactions.
-It can also be used for the preparation of photochromic materials, dyes and fungicides.
Preparation Method:
- 4-Nitrobenzene-1,3-diol can be prepared by nitration of p-nitrophenol. First, nitrobenzene and concentrated sulfuric acid are mixed, heated to an appropriate temperature, and after a period of reaction, water is added to stop the reaction. After that, 4-Nitrobenzene-1,3-diol was obtained by crystallization purification.
Safety Information:
- 4-Nitrobenzene-1,3-diol is dangerous and should be handled with care.
-It may cause irritation or damage to the eyes, skin, respiratory and digestive systems.
-Wear appropriate protective equipment such as gloves, glasses and protective clothing during use or handling.
-Avoid inhaling its dust or contact with the skin.
-If inhaled or ingested by mistake, seek medical attention immediately and explain to your doctor with a label on the packaging or chemical.
Last Update：2024-04-10 22:29:15
