3184-13-2
L(+)-Ornithine hydrochloride
CAS: 3184-13-2
Molecular Formula: C5H13ClN2O2
3184-13-2 - Names and Identifiers
| Name | L(+)-Ornithine hydrochloride |
| Synonyms | L-ORN HCL H-Orn-OH.HCl H-Orn-OH*HCl H-Orn-OH·HCl L-Ornithine HCl L-Ornithine.Hcl L-ORNITHINE HCL L-Ornithine, HCl L-ORNITHINE-OH HCL Ornithine hydrochloride L-Ornithine hydrochloride L-ORNITINE MONOCHLORHYDRATE L(+)-Ornithine hydrochloride L(+)-ORNITHINE HYDROCHLORIDE (2S)-2,5-diammoniopentanoate L(+)-Ornithine Hydrochloride L-ORNITHINE-OH HYDROCHLORIDE L-Ornithine Monohydrochloride L-ORNITHINE MONOHYDROCHLORIDE L-ORNITHINE HYDROCHLORIDE SALT L-(+)-ORNITHINE MONOHYDROCHLORIDE L-ornithine hcl cell culture tested (S)-(+)-2,5-Diaminopentanoic acid hydrochloride |
| CAS | 3184-13-2 |
| EINECS | 221-678-6 |
| InChI | InChI=1/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/p+1/t4-/m0/s1 |
| InChIKey | GGTYBZJRPHEQDG-WCCKRBBISA-N |
3184-13-2 - Physico-chemical Properties
| Molecular Formula | C5H13ClN2O2 |
| Molar Mass | 168.62 |
| Density | 1.57 |
| Melting Point | 245°C (dec.)(lit.) |
| Boling Point | 308.7°C at 760 mmHg |
| Specific Rotation(α) | 24 º (c=4, 6N HCl) |
| Flash Point | 140.5°C |
| JECFA Number | 2120 |
| Water Solubility | Soluble in water (543 mg/ml at 20°C), and alcohol. |
| Solubility | Solubility in water: 543G/L (20 C), soluble in inorganic acid; Insoluble in most organic solvents |
| Vapor Presure | 0.00015mmHg at 25°C |
| Appearance | White crystal |
| Color | White |
| Maximum wavelength(λmax) | ['λ: 260 nm Amax: 0.06', , 'λ: 280 nm Amax: 0.06'] |
| Merck | 14,6874 |
| BRN | 3625847 |
| PH | 5.0-6.0 (25℃, 1M in H2O) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Stability | Stable. |
| Sensitive | Easily absorbing moisture |
| Refractive Index | 24 ° (C=4, 6mol/L HC |
| MDL | MFCD0006452 |
| Physical and Chemical Properties | density 1.57 |
| In vivo study | L-Ornithine and phenylacetate act synergistically in pigs with acute liver failure to slow the increase in arterial blood ammonia, significantly reduce extracellular brain ammonia, and prevent increased intracranial pressure. |
3184-13-2 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | RM2985000 |
| FLUKA BRAND F CODES | 3-10 |
| TSCA | Yes |
| HS Code | 29224995 |
| Toxicity | LD50 orl-rat: 10 g/kg JPMSAE 62,49,73 |
3184-13-2 - Reference
| Reference Show more | 1. Hu Cuicui, Li Qiuyan, Zhu Xiaojuan, etc. Isolation and identification of biogenic amine-producing bacteria from rice wine Koji [J]. Food Research and Development, 2017(19):170-174. 2. Ma linlong Liu Yanli Cao Dan Liu Panpan Wang Shengpeng Huang Yong Ming Jin Xiaofang. Analysis and evaluation model construction of different tea varieties (lines) of green tea taste [J]. Journal of Agricultural Engineering 2020 36(10):277-286. 3. [IF = 4.939] Lili Wen et al."Protein Aggregation and Performance Optimization Based on Microconformational Changes of Aromatic hydrophonic Regions." Mol Pharmaceut. 2018;15(6):2257-2267 4. [IF = 4.379] Feng Lin et al."Chemical profile changes during pile fermentation of Qingzhuan tea affect inhibition of α-amylase and lipase."Sci Rep-Uk. 2020 Feb;10(1):1-10 5. [IF=3.361] Ruixue Yu et al."Targeted neurotransmitter metabolomics profiling of oleanolic acid in the treatment of spontaneously hypertensive rats."Rsc Adv. 2019 Jul;9(40):23276-23288 |
3184-13-2 - Nature
Open Data Verified Data
- This product is white crystalline powder, melting point 226~227 ℃, soluble in water, insoluble in methanol, ethanol and ether. Specific rotation +11. (5.5%,23 degrees C).
- ornithine is not a constituent of protein, but participates in the ornithine cycle of human body, and can promote the generation of polyamine compounds such as putrescine, spermidine and spermine in vivo, the latter is an important substance that promotes cell proliferation. This product has the activation of ornithine cycle, promote liver ammonia toxicity.
Last Update：2024-01-02 23:10:35
3184-13-2 - Use
Open Data Verified Data
amino acid drugs. Can activate the ornithine cycle, promote the liver ammonia toxicity. It is used together with L-arginine, L-citrulline and the like as an antidote and a liver function promoter.
Last Update：2022-01-01 11:10:31
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View History
3184-13-2
(AZETIDIN-2-YL)METHANAMINE
双(1-(2,4-二氟苯基)-3-吡咯基)二茂钛
丙二酸单甲酯酰氯
dimethyl-heptyl tetrahydrocannabinol
3-氟-4-氟乙酰苯胺
H-D-Val-OMe·HCl
3-cyclopentene-1-Methyl
烯丙基季戊四醇
2-Acetylamino-2-deoxy-5-O,6-O-isopropylidene-D-gluconic acid methyl ester
(AZETIDIN-2-YL)METHANAMINE
双(1-(2,4-二氟苯基)-3-吡咯基)二茂钛
丙二酸单甲酯酰氯
dimethyl-heptyl tetrahydrocannabinol
3-氟-4-氟乙酰苯胺
H-D-Val-OMe·HCl
3-cyclopentene-1-Methyl
烯丙基季戊四醇
2-Acetylamino-2-deoxy-5-O,6-O-isopropylidene-D-gluconic acid methyl ester