320581-09-7 - Names and Identifiers
Name | tert-butyl (1-amino-2-methylpropan-2-yl)carbamate
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Synonyms | Anagliptin Impurity 6 tert-Butyl (1-amino-2-methylpropan-2-yl)carbamate tert-butyl (1-amino-2-methylpropan-2-yl)carbamate (2-Amino-tert-butyl)carbamic acid tert-butyl ester (2-Amino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester N-(1-amino-2-methylpropan-2-yl)carbamic acid tert-butyl ester Carbamicacid,N-(2-amino-1,1-dimethylethyl)-,1,1-dimethylethylester Carbamic Acid, (2-Amino-1,1-Dimethylethyl)-, 1,1-Dimethylethyl Ester* Carbamic acid, (2-amino-1,1-dimethylethyl)-, 1,1-dimethylethyl ester (9CI)
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CAS | 320581-09-7
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320581-09-7 - Physico-chemical Properties
Molecular Formula | C9H20N2O2
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Molar Mass | 188.27 |
Density | 0.974 |
Boling Point | 275℃ |
Flash Point | 120℃ |
pKa | 12.74±0.46(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
320581-09-7 - Introduction
tert-butyl carbamate, also known as tert-butyl carbamate, is an organic compound. Its molecular formula is C9H20N2O2, and its structure contains an amino group and a carbamate group, as well as two butyl substituents.
Nature:
-Appearance: Colorless or light yellow liquid
-Density: approx. 0.93g/cm3
-Melting point: no clear data
-Boiling point: About 230-250 ℃
-Solubility: Soluble in organic solvents such as alcohols, ethers and ketones, insoluble in water
Use:
tert-butyl carbamate, as an organic synthesis intermediate, is widely used in chemical synthesis and drug development. It is often used as a raw material for the preparation of a wide variety of organic compounds, such as pharmaceutically active compounds, dyes and pesticides.
Method:
tert-butyl carbamate can be prepared by the following steps:
1. First, tert-butyl chloroformate (tert-butyl) is reacted with dimethylamine to obtain dimethylamine tert-butyrate (tert-butyl).
2. Subsequently, dimethylamine tert-butyrate is reacted with tert-butylamine to generate tert-butyl carbamate.
Safety Information:
Regarding tert-butyl (carbamate) safety information, you need to pay attention to the following points:
-It may be irritating to the eyes, skin and respiratory system, so wear appropriate protective equipment such as safety glasses, gloves and respiratory protection during operation.
-Avoid breathing its vapor or contact with its liquid. In case of contact, immediately wash the affected area with plenty of water and seek medical attention if necessary.
-When storing and handling, keep away from ignition and oxidizing agents to prevent fire and explosion accidents.
-Before use, please read the Safety Data Sheet (MSDS) of the compound carefully and follow the corresponding operating procedures.
Last Update:2024-04-09 21:01:54