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32476-67-8

periplocymarin

CAS: 32476-67-8

Molecular Formula: C30H46O8

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32476-67-8 - Names and Identifiers

Name periplocymarin
Synonyms periplocymarin
Card-20(22)-enolide, 3-[(2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-, (3β,5β)- (9CI)
4-[(3S,5S,10R,13R,14S,17S)-5,14-dihydroxy-3-[(2S,5R)-5-hydroxy-4-methoxy-6-methyl-oxan-2-yl]oxy-10,13-dimethyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-5H-furan-2-one
CAS 32476-67-8

32476-67-8 - Physico-chemical Properties

Molecular FormulaC30H46O8
Molar Mass534.68
Density1.27±0.1 g/cm3(Predicted)
Melting Point148°
Boling Point690.9±55.0 °C(Predicted)
Specific Rotation(α)D27 +29° (c = 0.94 in 95% alcohol for the anhydr substance)
Solubility Soluble in chloroform, ethyl acetate, soluble in methanol, DMSO
AppearanceWhite powder
pKa13.55±0.70(Predicted)
Storage Condition2-8℃
MDLMFCD01740198
Physical and Chemical PropertiesWhite crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the skin.
In vitro study Periplocymarin inhibits proliferation of PC3, U937, HCT-8, Bel-7402, BGC823, A549, and A2780 cell lines in vitro with IC 50 values of 0.02-0.29 µM.

32476-67-8 - Reference

Reference
Show more
1. [IF=4.36] Lei Chen et al."Chemical profiling and the potential active constituents responsible for wound healing in Periploca forrestii Schltr."J Ethnopharmacol. 2018 Oct;224:230
2. [IF=3.414] Jinsong Li et al."Effects of Periploca forrestii Schltr on wound healing by Src meditated Mek/Erk and PI3K/Akt signals."J Ethnopharmacol. 2019 Jun;237:116

32476-67-8 - Reference Information

biological activity Periplocymarin is a cardiac glycoside isolated from Periploca sepium and Periploca graeca, is a potential anti-cancer compound.
Last Update:2024-04-09 02:00:12
32476-67-8
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View History
32476-67-8
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