325-50-8

325-50-8 - Names and Identifiers

Name	5-Fluoro-2-methylphenylhydrazine hydrochloride
Synonyms	(5-fluoro-2-methylphenyl)hydrazine 5-Fluoro-2-methylphenylhydrazineHCl 4-Fluoro-2-hydrazinotoluene hydrochloride (5-fluoro-2-methylphenyl)diazanium chloride 5-FLUORO-2-METHYLPHENYLHYDRAZINE HYDROCHLORIDE 5-Fluoro-2-methylphenylhydrazine hydrochloride 3-Fluoro-6-(Methyl)phenylhydrazine hydrochloride 1-(5-FLUORO-2-METHYLPHENYL)HYDRAZINE HYDROCHLORIDE 4-Fluoro-2-hydrazinotoluene hydrochloride, 4-Fluoro-2-hydrazino-1-methylbenzene hydrochloride
CAS	325-50-8
InChI	InChI=1/C7H9FN2/c1-5-2-3-6(8)4-7(5)10-9/h2-4,10H,9H2,1H3

325-50-8 - Physico-chemical Properties

Molecular Formula	C7H10ClFN2
Molar Mass	176.62
Density	1.202g/cm³
Melting Point	197°C (dec.)
Boling Point	212°C at 760 mmHg
Flash Point	82°C
Vapor Presure	0.177mmHg at 25°C
BRN	3696216
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.594
MDL	MFCD00053032

325-50-8 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R20/22 - Harmful by inhalation and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	2811
Hazard Note	Irritant
Packing Group	II

325-50-8 - Introduction

hydrochloride is an organic compound with the chemical formula C7H9FN2 · HCl. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline powder
-Melting point: about 170-174 ° C
-Solubility: Soluble in water and general organic solvents

Use:
-hydrochloride can be used as an important intermediate and reagent in the chemical synthesis process.
-It can be used to synthesize fluorinated aromatic amines and other organic compounds.

Method:
The synthesis of hydrochloride is usually obtained by reacting 5-Fluoro-2-methylphenylhydrazine with hydrogen chloride in toluene.
-First, heat and dissolve 5-fluoro-2-methylphenylhydrazine in toluene, and then gradually add hydrogen chloride gas, and the reaction proceeds for several hours.
-Filter the solid, mix its hypoacetate with n-heptane and cool to obtain crystals of hydrochloride.
-Finally, the pure product is obtained through the steps of filtration, drying and recrystallization.

Safety Information:
-The hydrochloride needs to pay attention to safety during operation.
-It is an organic compound with certain toxicity and irritation. Direct contact with skin and inhalation should be avoided.
-Wear appropriate protective equipment, such as gloves, goggles and protective masks, when in use.
-Try to operate in a well-ventilated place and avoid dust in the air.
-Waste disposal should be carried out in accordance with local regulations, do not discharge or mix other chemicals.

Last Update：2024-04-10 22:29:15