325704-15-2
2-[(Carboxymethyl)sulfanyl]nicotinic acid
CAS: 325704-15-2
Molecular Formula: C8H7NO4S
325704-15-2 - Names and Identifiers
325704-15-2 - Physico-chemical Properties
| Molecular Formula | C8H7NO4S |
| Molar Mass | 213.21 |
| Melting Point | 216-218°C |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD02250402 |
325704-15-2 - Risk and Safety
| Hazard Class | IRRITANT |
325704-15-2 - Introduction
2-[(Carboxymethyl)sulfanyl]nicotinic acid, also known as carbomethylthio nicotinic acid, is an organic compound with a chemical formula of C8H8NO4S.
Nature:
Carbomethylthio nicotinic acid is a colorless to yellow crystalline powder. It is soluble in water and some organic solvents at room temperature and has acidity. It is a neutral to acidic substance with a pKa of 3.97.
Use:
Carbomethylthionicotinic acid is commonly used as a raw material or intermediate of drugs, and has a variety of applications in medicine and health care. It can be used to treat cardiovascular diseases, metabolic diseases and neurological diseases. In addition, carbomethylthionicotinic acid can also be used in the fields of food, feed and cosmetics.
Preparation Method:
The preparation method of carbomethylthionicotinic acid can be obtained by the transesterification reaction between thioacetic acid and 2-aminonicotinic acid. A specific method involves reacting 2-aminonicotinic acid with a thioacetate ester, followed by acid hydrolysis to obtain the desired product.
Safety Information:
Carbomethylthionicotinic acid is relatively stable under normal conditions, but avoid contact with strong oxidants. In the process of use, should follow the relevant safety procedures, such as wearing protective gloves, glasses and protective clothing, and ensure a good ventilation environment. In the event of an accident such as inhalation, contact with skin or eyes, wash immediately and seek medical help if necessary.
Nature:
Carbomethylthio nicotinic acid is a colorless to yellow crystalline powder. It is soluble in water and some organic solvents at room temperature and has acidity. It is a neutral to acidic substance with a pKa of 3.97.
Use:
Carbomethylthionicotinic acid is commonly used as a raw material or intermediate of drugs, and has a variety of applications in medicine and health care. It can be used to treat cardiovascular diseases, metabolic diseases and neurological diseases. In addition, carbomethylthionicotinic acid can also be used in the fields of food, feed and cosmetics.
Preparation Method:
The preparation method of carbomethylthionicotinic acid can be obtained by the transesterification reaction between thioacetic acid and 2-aminonicotinic acid. A specific method involves reacting 2-aminonicotinic acid with a thioacetate ester, followed by acid hydrolysis to obtain the desired product.
Safety Information:
Carbomethylthionicotinic acid is relatively stable under normal conditions, but avoid contact with strong oxidants. In the process of use, should follow the relevant safety procedures, such as wearing protective gloves, glasses and protective clothing, and ensure a good ventilation environment. In the event of an accident such as inhalation, contact with skin or eyes, wash immediately and seek medical help if necessary.
Last Update：2024-04-09 15:18:09
