Molecular Formula | C14H12O3S
|
Molar Mass | 260.31 |
Density | 1.2959 (rough estimate) |
Melting Point | 96° (isopropyl ether) |
Boling Point | 373.57°C (rough estimate) |
Solubility | Practically insoluble in water, freely soluble in acetone, in ethanol (96 per cent) and in methylene chloride. |
Appearance | neat |
Color | White to Almost white |
Maximum wavelength(λmax) | ['314nm(Phosphate buffer sol.)(lit.)'] |
Merck | 14,9422 |
pKa | 4.05±0.10(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.5050 (estimate) |
In vivo study | Female Lewis rats received either Tiaprofenic acid (as an intravenous (iv.) bolus injection of 15 mg/kg and constant infusion of 0.02 mg/min) for 6 h. Tiaprofenic acid results in a significant decrease in serum sulfate concentrations and increase in sulfate clearance ratio. There is also a significant decrease in the fraction of sulfate reabsorbed by the kidneys. |