331-30-6 - Names and Identifiers
331-30-6 - Physico-chemical Properties
Molecular Formula | C9H10FNO
|
Molar Mass | 167.18 |
331-30-6 - Introduction
N-(4-fluoro-3-methylphenyl)-Acetamide is an organic compound with the formula C10H10FNO. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: N-(4-fluoro-3-methylphenyl)-Acetamide is a white crystalline solid.
-Melting point: About 75-77 degrees Celsius.
-freezing point: about 112-115 degrees Celsius.
-Solubility: N-(4-fluoro-3-methylphenyl)-Acetamide is soluble in organic solvents such as ethanol and methanol, and slightly soluble in water.
Use:
N-(4-fluoro-3-methylphenyl)-Acetamide has certain application value in the field of medicine, and is often used as an intermediate or raw material. It can be used to synthesize some pharmaceutical intermediates, such as antibiotics, anti-inflammatory drugs and so on.
Method:
There are many preparation methods of N-(4-fluoro-3-methylphenyl)-Acetamide, and a common synthetic route is as follows:
First, 2-fluoro-5-acetanilide is obtained by reacting 2-fluoroaniline with acetic anhydride. Then, under the catalysis of a base, 2-fluoro-5-acetanilide reacts with formaldehyde to give N-(4-fluoro-3-methylphenyl)-Acetamide.
Safety Information:
N-(4-fluoro-3-methylphenyl)-Acetamide is generally relatively safe when used and stored correctly. However, as a chemical, it still needs to be handled with caution. In case of contact with skin, eyes or respiratory tract, rinse immediately with water and seek medical help. During use, please observe the relevant safety regulations, wear appropriate protective equipment, and ensure that the operating area is well ventilated. At the same time, store chemicals in a dry, cool, well-ventilated place, and away from fire and flammable materials.
Last Update:2024-04-09 21:11:58