331834-13-0 - Names and Identifiers
331834-13-0 - Physico-chemical Properties
Molecular Formula | C8H7BO3
|
Molar Mass | 161.95 |
Density | 1.31±0.1 g/cm3(Predicted) |
Boling Point | 340.4±34.0 °C(Predicted) |
Flash Point | 159.7°C |
Vapor Presure | 3.33E-05mmHg at 25°C |
pKa | 8.25±0.30(Predicted) |
Storage Condition | Inert atmosphere,2-8°C |
Refractive Index | 1.618 |
331834-13-0 - Risk and Safety
Hazard Symbols | C - Corrosive
|
Hazard Note | Corrosive |
331834-13-0 - Introduction
1-benzofuran-5-ylboronic acid, chemical formula C8H7BO3, is an organic boron compound. The following is a description of its nature, use, formulation and safety information:
Properties: 1-benzofuran-5-ylboronic acid is a solid compound, usually a white crystal or crystal powder. It has good stability at room temperature and good solubility. It is a weak acid that can react with alkali or metal to form the corresponding salt.
Purpose: 1-benzofuran-5-ylboronic acid is an important reagent and intermediate in organic synthesis. It can be used as a substrate for palladium-catalyzed coupling reactions, such as the coupling reaction of 1-benzofuran-5-ylboronic acid with aromatic halides in the presence of bases to generate new aromatic compounds. In addition, it can also be used in drug synthesis and other organic synthesis processes.
Preparation method: 1-benzofuran-5-ylboronic acid can be prepared by reacting benzofuran with boronic acid under alkaline conditions. A common method of preparation is the reaction of benzofuran and boronic acid in alkaline solution by heating, followed by acidification to obtain the product.
Safety Information: 1-benzofuran-5-ylboronic acid is generally considered to be a relatively safe compound. However, it is an irritant and may be irritating to the eyes, skin and mucous membranes. Therefore, appropriate personal protective measures should be taken during handling and use, such as wearing gloves, goggles and laboratory coats. In addition, avoid contact with strong oxidants and strong acids to avoid dangerous reactions.
Last Update:2024-04-09 20:48:19