332154-57-1 - Names and Identifiers
332154-57-1 - Physico-chemical Properties
Molecular Formula | C7H6BClO3
|
Molar Mass | 184.38 |
Density | 1.39±0.1 g/cm3(Predicted) |
Melting Point | >300℃ |
Boling Point | 350.9±44.0 °C(Predicted) |
pKa | 7.08±0.10(Predicted) |
332154-57-1 - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
332154-57-1 - Introduction
(4-Chlorocarbonylphenyl)boronic anhydride is an organic compound with the chemical formula C8H6BClO3. It is a solid powder with a strong pungent smell. The following is an introduction to some properties, uses, methods and safety information about (4-Chlorocarbonylphenyl)boronic anhydride:
Nature:
-Appearance: white or off-white solid powder
-Melting point: About 80-85 ℃
-Boiling point: About 180 ℃
-Soluble: Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methylene chloride (DCM)
-Stability: stable under dry conditions, but may be hydrolyzed in moisture
Use:
(4-Chlorocarbonylphenyl)boronic anhydride is commonly used in Suzuki coupling reactions in organic synthesis reactions. It can be used as an intermediate in organic synthesis for the synthesis of drugs, pesticides and other organic compounds.
Method:
It can be prepared by reacting (4-Chlorocarbonylphenyl)boronic anhydride with potassium hydroxide in a solvent. The preparation process generally needs to be carried out under an inert atmosphere and requires a certain temperature and time.
Safety Information:
- (4-Chlorocarbonylphenyl)boronic anhydride is an irritant compound that may cause irritation and allergic reactions in contact with the skin or by inhalation of its dust. Avoid contact with skin, eyes and respiratory tract during operation, and use appropriate personal protective equipment.
-During use and storage, avoid contact with oxidants and strong acids to avoid dangerous reactions.
-It should be operated in a well-ventilated place and avoid inhaling its dust.
-In case of accidental inhalation or skin contact, immediately move to an air circulation area, rinse with water, and seek medical help.
The information provided above is for reference only. Users should carefully read the Safety Data Sheet (MSDS) of the relevant chemical before operation and follow the correct experimental procedures.
Last Update:2024-04-09 15:17:56