3338-32-7
Z-L-aspartic acid 4-tert-butyl-1-(N-succinimidyl) ester
CAS: 3338-32-7
Molecular Formula: C20H24N2O8
3338-32-7 - Names and Identifiers
| Name | Z-L-aspartic acid 4-tert-butyl-1-(N-succinimidyl) ester |
| Synonyms | Z-ASP(OBUT)-OSU Z-Asp(OtBu)-OSu Z-Asp(Otbu)-Osu Z-ASP(OTBU)-OSU Z-ASPARTIC ACID(OTBU)-OSU Z-L-aspartic acid 4-tert-butyl-1-(N-succinimidyl) ester Z-ASPARTIC ACID TERT-BUTYL ESTER HYDROXYSUCCINIMIDE ESTER N-CBZ-BETA-TERT-BUTYL-L-ASPARTIC ACID N-HYDROXYSUCCINIMIDE ESTER Z-L-ASPARTIC ACID BETA-T-BUTYL ESTER ALPHA-N-HYDROXYSUCCINIMIDE ESTER N-BENZYLOXYCARBONYL-L-ASPARTIC ACID 4-TERT-BUTYL-1-(N-SUCCINIMIDYL) ESTER (S)-4-tert-Butyl 1-(2,5-dioxopyrrolidin-1-yl)-2-(((benzyloxy)carbonyl)amino)succinate |
| CAS | 3338-32-7 |
| EINECS | 222-080-8 |
| InChI | InChI=1/C20H24N2O8/c1-20(2,3)29-17(25)11-14(18(26)30-22-15(23)9-10-16(22)24)21-19(27)28-12-13-7-5-4-6-8-13/h4-8,14H,9-12H2,1-3H3,(H,21,27) |
3338-32-7 - Physico-chemical Properties
| Molecular Formula | C20H24N2O8 |
| Molar Mass | 420.41 |
| Density | 1.32±0.1 g/cm3(Predicted) |
| Melting Point | 150-152°C |
| Appearance | Powder |
| Color | White to off-white |
| pKa | 10.03±0.46(Predicted) |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
| Refractive Index | 1.559 |
3338-32-7 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10-21 |
3338-32-7 - Introduction
Z-L-aspartic acid 4-tert-butyl-1-(N-succinimidyl) ester is a compound with the chemical formula C25H30N2O9.
Properties of the compound:
-Appearance: Colorless to light yellow solid
-Melting Point: about 105-110 ℃
-Solubility: Soluble in organic solvents such as dichloromethane, ethanol and DMF, etc., insoluble in water.
The main uses of the compound are as follows:
1. Protecting group in organic synthesis: As a compound to protect amino acids, the protecting group can be removed by enzymatic hydrolysis or alkaline hydrolysis to restore the activity of amino acids.
2. Drug research: can be used for the synthesis of peptide drugs or peptide drug intermediates.
Preparation Method:
The synthesis of this compound can be obtained by reacting an N-protected amino acid with an appropriate succinic acid iminylation reagent. The specific synthesis method may vary according to the experimental conditions and the purity requirements of the desired product, and the commonly used reaction conditions include suitable solvents and catalysts, and at an appropriate temperature and reaction time.
Safety Information:
1. The compound belongs to organic synthesis reagent, need to pay attention to safe operation, avoid direct contact with skin and eyes. Appropriate personal protective equipment should be worn during laboratory operations.
2. For the use of any chemical, it should be handled and stored in accordance with the safety operation guidelines and MSDS (safety data sheet).
3. The compound may have certain toxicity to human body, such as ingestion or inhalation, please seek medical treatment immediately and bring the detailed information of the compound.
Properties of the compound:
-Appearance: Colorless to light yellow solid
-Melting Point: about 105-110 ℃
-Solubility: Soluble in organic solvents such as dichloromethane, ethanol and DMF, etc., insoluble in water.
The main uses of the compound are as follows:
1. Protecting group in organic synthesis: As a compound to protect amino acids, the protecting group can be removed by enzymatic hydrolysis or alkaline hydrolysis to restore the activity of amino acids.
2. Drug research: can be used for the synthesis of peptide drugs or peptide drug intermediates.
Preparation Method:
The synthesis of this compound can be obtained by reacting an N-protected amino acid with an appropriate succinic acid iminylation reagent. The specific synthesis method may vary according to the experimental conditions and the purity requirements of the desired product, and the commonly used reaction conditions include suitable solvents and catalysts, and at an appropriate temperature and reaction time.
Safety Information:
1. The compound belongs to organic synthesis reagent, need to pay attention to safe operation, avoid direct contact with skin and eyes. Appropriate personal protective equipment should be worn during laboratory operations.
2. For the use of any chemical, it should be handled and stored in accordance with the safety operation guidelines and MSDS (safety data sheet).
3. The compound may have certain toxicity to human body, such as ingestion or inhalation, please seek medical treatment immediately and bring the detailed information of the compound.
Last Update：2024-04-09 19:05:49
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CAS: 3338-32-7
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Mobile: 18021002903
QQ: 3008007409
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CAS: 3338-32-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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