3387-36-8
Uridine 5-monophosphate, disodium salt
CAS: 3387-36-8
Molecular Formula: C9H11N2Na2O9P
3387-36-8 - Names and Identifiers
| Name | Uridine 5-monophosphate, disodium salt |
| Synonyms | UMP 2NA UMP, NA2 5'-UMP-NA2 5'-UMP,2Na UMP DISODIUM 5'-URIDYLIC ACID UMP DISODIUM SALT U 5'-P DISODIUM SALT 5'-O-phosphonatouridine 5'-URIDYLIC ACID DISODIUM SALT 5'-Uridylic Acid Disodium Salt disodium 5'-O-phosphonatouridine Disodium Uridine-5'-Monophosphate Uridine-5'-Monophosphate Disodium Salt Uridine-5'-monophosphate,disodium salt Uridine 5-monophosphate, disodium salt Uridine 5'-monophosphate, disodium salt Uridine-5'-phosphoric acid disodium salt Uridine-5'-monophsphosphoric acid, disodium salt disodium 1-(5-O-phosphonato-beta-D-arabinofuranosyl)pyrimidine-2,4(1H,3H)-dione |
| CAS | 3387-36-8 |
| EINECS | 222-211-9 |
| InChI | InChI=1/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/p-2/t4-,6-,7-,8-/m1/s1 |
| InChIKey | KURVIXMFFSNONZ-WFIJOQBCSA-L |
3387-36-8 - Physico-chemical Properties
| Molecular Formula | C9H11N2Na2O9P |
| Molar Mass | 368.14 |
| Melting Point | 208-210 °C |
| Specific Rotation(α) | -14 ° (C=1, H2O) |
| Water Solubility | 40 g/100 mL (20 ºC) |
| Solubility | Easily soluble in water (41g/100 m1), slightly soluble in methanol, insoluble in ethanol. |
| Appearance | Colorless to white crystal or white crystalline powder |
| Color | White |
| BRN | 3582885 |
| pKa | 6.4, 9.5(at 25℃) |
| Storage Condition | 2-8°C |
| Stability | Very Hygroscopic |
| Sensitive | Easily absorbing moisture |
| Refractive Index | -14 ° (C=1, H2O) |
| MDL | MFCD00006525 |
| Physical and Chemical Properties | Properties: This product is white or white powder, no normal visual acuity visible impurities; Odorless, tasteless, with hygroscopicity. Storage: light-shielding sealed cool storage |
| Use | Can be used as the production of nucleic acid drug intermediates, health food and biochemical reagents, and used in the manufacture of uridine triphosphate (UTP), polyglandular urine, fluoride and other drugs. |
3387-36-8 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 2 |
| RTECS | YU7975000 |
| FLUKA BRAND F CODES | 10-21 |
| HS Code | 29389090 |
3387-36-8 - Reference
| Reference Show more | Analysis of flavor components in 5 kinds of fresh edible fungi by HPLC HS-SPME-GC-MS [J]. Food Industry Science & Technology 2019 040(003):254-260. |
3387-36-8 - Reference Information
| introduction | disodium uridylate, also known as disodium 5 '-uridylate, can be used as an important intermediate for the production of nucleic acid drugs, health food and biochemical reagents. It is also used to manufacture uridine diphosphate glucose, uridine triphosphate, polyuridine acid and other drugs, and plays an important role in the treatment of many major diseases. |
| identification test | take 20mg of sample and dissolve it in 100ml of 0.01mol/L hydrochloric acid. Take 10ml of the solution and add 0.01mol/L hydrochloric acid to 100ml. The solution has a maximum absorption value at 262nm ± 2nm. Positive for sodium salt reaction (IT-28). Take 3ml of 0.03% sample aqueous solution, add 1ml of hydrochloric acid and 1ml of bromine test solution (TS-46), heat in a water bath for 30min, blow in air to remove excess bromine, add O.2ml of ethanol solution 10% dihydroxytoluene and 3ml of ammonium ferric sulfate hydrochloric acid test solution (TJH 100), and heat in a water bath for 20min, it should be green. Take 5ml of (1+20) sample aqueous solution and add 2ml of magnesium oxygen test solution (TS-133) without precipitation. Add 7ml of nitric acid, boil for 10min and neutralize with sodium hydroxide solution (TS-224). The phosphate test (IT-26) should be positive. |
| content analysis | weigh the sample accurately about 500mg, use 0.01mol/L hydrochloric acid to fix the volume to 1000ml, take 10ml of the solution, and then use 0.01mol/L hydrochloric acid to fix the volume to 250ml. 0.01mol/L hydrochloric acid solution was used as control, and absorbance A was measured at 260nm with a width of 1cm. The content of disodium uridylate (C9H11N2Na2O9P) in the sample is calculated according to the following formula: content (%)= 500./sample size (mg)× 185.9A/(100-moisture (%))× 100 |
| toxicity | LD50 (rat, oral)>10 g/kg; No abnormalities were found in rats after subacute, chronic, teratogenic mutation and reproduction tests. |
| use | flavoring agent. Add milk to increase the amount of nucleotides to make it close to human milk ingredients and enhance the resistance of infants and young children. adjuvant medicine for liver disease. It can be used as an intermediate in the production of nucleic acid drugs, health food and biochemical reagents, and used in the production of uridine triphosphate (UTP), polyadenuria, fluoroiron and other drugs. |
| production method | nucleic acid is extracted from yeast first, then separated by nuclease decomposition and ion exchange resin, and then concentrated and crystallized with sodium hydroxide. |
Last Update：2024-04-09 19:05:11
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