Name | SUGAMMADEX |
Synonyms | Bridion Org 25969 SUGAMMADEX Sugammagex Shu Glucose Unii-361lpm2T56 Sugammadex [inn] SugaMMadex SodiuM |
CAS | 343306-71-8 |
EINECS | 253-874-2 |
Molecular Formula | C72H112O48S8 |
Molar Mass | 2002.15 |
Density | 1.559±0.06 g/cm3(Predicted) |
Melting Point | >208°C (dec.) |
Solubility | Aqueous Acid (Slightly), Water (Slightly, Sonicated) |
Appearance | Solid |
Color | White to Pale Beige |
pKa | 3.42±0.10(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Stability | Hygroscopic |
muscle relaxant antagonist | , the US FDA approved the new drug Sugammadex (trade name Bridion) of the Netherlands Organon through the priority approval route. It is used to rapidly reverse the neuromuscular blockade caused by the anaesthetics rocuronium bromide and vecuronium bromide during surgery in adult patients. Sugengglucose is a synthetic Modified γ-cyclodextrin consisting of a lipophilic core and a hydrophilic outer end. Sugengglucose administered by intravenous injection can significantly improve the recovery of muscle relaxation after surgery, the rapid reversal of neuromuscular blockade by steroid muscle relaxants in a short period of time is of positive significance for improving the safety of general anesthesia. |