34542-56-8
17,21-dihydroxy-16alpha-methylpregna-4,9(11)-diene-3,20-dione 21-acetate
CAS: 34542-56-8
Molecular Formula: C24H32O5
34542-56-8 - Names and Identifiers
34542-56-8 - Physico-chemical Properties
| Molecular Formula | C24H32O5 |
| Molar Mass | 400.52 |
| Density | 1.21±0.1 g/cm3(Predicted) |
| Melting Point | 205-208 °C |
| Boling Point | 555.4±50.0 °C(Predicted) |
| pKa | 12.50±0.70(Predicted) |
| Physical and Chemical Properties | Chemical properties crystallization (methanol). Melting point> 198 ℃. |
| Use | Use an intermediate of dexamethasone acetate. |
34542-56-8 - Production method
You can use 3 β-hydroxygestrol -5,16-diene -20-keto -3-acetate (that is, gestational dienolone acetate) via (16-position double bond and nitrosomethyl Urea) is added and eliminated to generate 3 β-hydroxy -16 β-methylgestrol -5,16-diene -20-keto -3-acetate, then (16-position double bond) epoxidation, (3-position hydroxyl) acetylation, (epoxy) ring opening (formation of 17 α-hydroxyl, 15-position double bond), catalytic hydrogenation, hydrolysis (removal of 3-position acetyl group), oxidation (3-position hydroxyl group to ketone group, the double bond is transferred to the 4-position), (21-position) iodination, (iodine atom is replaced by acetoxy), biological oxidation (formation of 11 α-hydroxyl group),(11 α-hydroxyl group) sulfonylation and elimination [formation 9,(11)-double bond] to obtain the product.
Last Update：2024-04-10 22:29:15
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Spot supply
Product Name: Clascoterone Impurity 13 Visit Supplier Webpage Request for quotationCAS: 34542-56-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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