35013-72-0
(+)-Biotin N-hydroxysuccinimide ester
CAS: 35013-72-0
Molecular Formula: C14H19N3O5S
35013-72-0 - Names and Identifiers
| Name | (+)-Biotin N-hydroxysuccinimide ester |
| Synonyms | IOTIN-NHS BIOTIN-NHS N-Hydroxysuccinimidobiotin (+)-Biotin N-hydroxysuccinimide ester 1-{[5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoyl]oxy}pyrrolidine-2,5-dione 1-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}oxy)pyrrolidine-2,5-dione |
| CAS | 35013-72-0 |
| EINECS | 609-055-0 |
| InChI | InChI=1/C14H19N3O5S/c18-10-5-6-11(19)17(10)22-12(20)4-2-1-3-9-13-8(7-23-9)15-14(21)16-13/h8-9,13H,1-7H2,(H2,15,16,21)/t8-,9-,13-/m0/s1 |
35013-72-0 - Physico-chemical Properties
| Molecular Formula | C14H19N3O5S |
| Molar Mass | 341.38 |
| Density | 1.45g/cm3 |
| Melting Point | 212-214 °C |
| Appearance | Morphological powder, color white to off-white |
| pKa | 13.89±0.40(Predicted) |
| Storage Condition | -20°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Refractive Index | 1.616 |
| MDL | MFCD00078531 |
| Physical and Chemical Properties | Bioactive Biotin NHS is an amino-reactive biotin reagent for the preparation of biotinylated surfaces or peptides. |
| Use | Use 1. Labeling of proteins, antigens, antibodies, nucleic acids (DNA, RNA), etc. 2, can be used for protein and peptide biotinylation, such as in the range of pH6.5-8.5 coupling to primary amines |
35013-72-0 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-23 |
| HS Code | 2934 99 90 |
35013-72-0 - Upstream Downstream Industry
35013-72-0 - Reference
| Reference Show more | Liu Hong, Maoxiang, Shuangliu Huan et al. Preparation of PEG-modified Fe_3O_4 nanoparticles (MNPs) and its catalytic oxidation of VB_1 [J]. Journal of Tianjin Agricultural University 2018. |
35013-72-0 - Introduction
This product is the most common NHS-ester biotin labeling reagent in cells, and the target position is intracellular protein. This product is N-hydroxysuccinimide biotin, which is the shortest of the three similar EZ-linked biotin succinimide ester reagents, which can make antibodies, proteins and other primary amine biomolecules in the solution simple and efficient Tagged reagents. This product can provide researchers with the possibility of optimizing labeling and detection experiments, in which the steric hindrance of biotin binding is an extremely important factor.
Last Update：2022-10-16 17:24:48
35013-72-0 - Application
NHS biotin reagents can perform simple and effective biotin labeling of antibodies, proteins and any other macromolecules containing primary amines in the solution. The three reagents differ only in the length of the spacer arm, providing researchers with the possibility of optimizing labeling and detection experiments, of which the steric hindrance of biotin binding is an important factor.
Last Update：2024-04-10 22:29:15
35013-72-0 - Nature
| solubility | DMF: ≤50 mg/mL Stable for at least one month in dry DMF |
| BRN | 4720781 |
Last Update：2024-04-09 01:59:50
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Spot supply
Product Name: NHS-Biotin Visit Supplier Webpage Request for quotationCAS: 35013-72-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
Raw Materials for 35013-72-0
1H-Imidazole, 1-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-
TSTU
D-Biotin
TSTU
D-Biotin
Downstream Products for 35013-72-0
biotinylamidoethylacetamide
LC-LC(+)-Biotin
N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE
D-BIOTINOL
(+)-BIOTIN-EPSILON-AMINOCAPROIC ACID
FMOC-LYS(BIOTIN)-OH
LC-LC(+)-Biotin
N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE
D-BIOTINOL
(+)-BIOTIN-EPSILON-AMINOCAPROIC ACID
FMOC-LYS(BIOTIN)-OH