350672-17-2
2-(Chloromethyl)-5-(2-fluorophenyl)-1,3,4-oxadiazole
CAS: 350672-17-2
Molecular Formula: C9H6ClFN2O
350672-17-2 - Names and Identifiers
350672-17-2 - Physico-chemical Properties
| Molecular Formula | C9H6ClFN2O |
| Molar Mass | 212.61 |
| Sensitive | Irritant |
| MDL | MFCD09041034 |
350672-17-2 - Introduction
2-(Cloromethyl)-5-(2-fluorophenyl)-1,3,4-oxadiazole is an organic compound with the chemical formula C9H6ClFN2O and a molecular weight of 200.61g/mol.
It is a white crystalline powder, soluble in chloroform and methanol, slightly soluble in dichloromethane and dimethyl sulfoxide, and almost insoluble in water. It has good thermal stability and chemical stability.
2-(Cloromethyl)-5-(2-fluorophenyl)-1,3,4-oxadiazole is commonly used as an intermediate in chemical synthesis. It has certain applications in the field of pharmaceuticals and pesticides. For example, it can be used to synthesize biologically active compounds, such as antibacterial and antitumor drugs.
The method for preparing 2-(Cloromethyl)-5-(2-fluorophenyl)-1,3,4-oxadiazole includes using a nucleophilic substitution reaction or an addition reaction, using 2-amino -5-(2-fluorophenyl)-1,3, 4-oxaline-4-carboxylic acid and methyl chloride as raw materials.
Regarding safety information, 2-(Cloromethyl)-5-(2-fluorophenyl)-1,3,4-oxadiazole is an organic compound and has certain toxicity. Care should be taken to prevent inhalation, contact with skin and eyes during handling and storage. Wear appropriate protective equipment such as gloves and goggles during use. At the same time, it is necessary to operate in a well-ventilated place to avoid the accumulation of harmful gases. In case of accidental contact, wash with soapy water immediately. Correct laboratory practices and safe operating procedures should be followed when handling this compound. If necessary, refer to the Safety Data Sheet of the relevant chemical.
It is a white crystalline powder, soluble in chloroform and methanol, slightly soluble in dichloromethane and dimethyl sulfoxide, and almost insoluble in water. It has good thermal stability and chemical stability.
2-(Cloromethyl)-5-(2-fluorophenyl)-1,3,4-oxadiazole is commonly used as an intermediate in chemical synthesis. It has certain applications in the field of pharmaceuticals and pesticides. For example, it can be used to synthesize biologically active compounds, such as antibacterial and antitumor drugs.
The method for preparing 2-(Cloromethyl)-5-(2-fluorophenyl)-1,3,4-oxadiazole includes using a nucleophilic substitution reaction or an addition reaction, using 2-amino -5-(2-fluorophenyl)-1,3, 4-oxaline-4-carboxylic acid and methyl chloride as raw materials.
Regarding safety information, 2-(Cloromethyl)-5-(2-fluorophenyl)-1,3,4-oxadiazole is an organic compound and has certain toxicity. Care should be taken to prevent inhalation, contact with skin and eyes during handling and storage. Wear appropriate protective equipment such as gloves and goggles during use. At the same time, it is necessary to operate in a well-ventilated place to avoid the accumulation of harmful gases. In case of accidental contact, wash with soapy water immediately. Correct laboratory practices and safe operating procedures should be followed when handling this compound. If necessary, refer to the Safety Data Sheet of the relevant chemical.
Last Update：2024-04-09 20:02:46
