351003-33-3
3-(4-bromophenyl)-6-methyl-2H-1,4-benzoxazine
CAS: 351003-33-3
Molecular Formula: C15H12BrNO
351003-33-3 - Names and Identifiers
| Name | 3-(4-bromophenyl)-6-methyl-2H-1,4-benzoxazine |
| Synonyms | 3-(4-bromophenyl)-6-methyl-2H-1,4-benzoxazine 2H-1,4-Benzoxazine,3-(4-bromophenyl)-6-methyl- |
| CAS | 351003-33-3 |
| EINECS | 604-604-1 |
| InChI | InChI=1/C15H12BrNO/c1-10-2-7-15-13(8-10)17-14(9-18-15)11-3-5-12(16)6-4-11/h2-8H,9H2,1H3 |
351003-33-3 - Physico-chemical Properties
| Molecular Formula | C15H12BrNO |
| Molar Mass | 302.17 |
| Density | 1.42±0.1 g/cm3(Predicted) |
| Melting Point | 86-90°C(lit.) |
| Boling Point | 401.9±45.0 °C(Predicted) |
| Flash Point | 196.9°C |
| Vapor Presure | 2.65E-06mmHg at 25°C |
| pKa | 4.08±0.20(Predicted) |
| Refractive Index | 1.636 |
351003-33-3 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
351003-33-3 - Introduction
3-(4-bromophenyl)-6-methyl-2H-1,4-benzoxazine is an organic compound containing a benzene ring and an oxazine ring in its chemical structure. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless solid
-Molecular formula: C15H11BrN
-Molecular weight: 294.16g/mol
-melting point: about 120-125 ℃
-Boiling point: about 350 ℃
-Solubility: Soluble in alcohol, chloroform and dichloromethane, insoluble in water.
Use:
3-(4-bromophenyl)-6-methyl-2H-1,4-benzoxazine is commonly used as an intermediate in organic synthesis. Because of its structure containing benzene ring and oxazine ring, the compound has potential application value in the field of medicine and material science. It can be used in the synthesis of chemicals and pharmaceutical intermediates, and also as a building block for organic light-emitting materials.
Preparation Method:
3-(4-bromophenyl)-6-methyl-2H-1,4-benzoxazine can be synthesized by a variety of methods. One commonly used method is the reaction of 4-bromoanisole with indole under basic conditions to yield the desired product.
Safety Information:
Because the hazard and toxicity of the compound have not been evaluated, appropriate protective measures should be taken when using or handling the compound. It is recommended to wear appropriate protective clothing, gloves and eye protection during operation to avoid contact with skin and inhalation. Be sure to operate under well-ventilated conditions to avoid inhaling vapors of the compound. Follow relevant safety procedures and comply with national and local regulations.
Nature:
-Appearance: Colorless solid
-Molecular formula: C15H11BrN
-Molecular weight: 294.16g/mol
-melting point: about 120-125 ℃
-Boiling point: about 350 ℃
-Solubility: Soluble in alcohol, chloroform and dichloromethane, insoluble in water.
Use:
3-(4-bromophenyl)-6-methyl-2H-1,4-benzoxazine is commonly used as an intermediate in organic synthesis. Because of its structure containing benzene ring and oxazine ring, the compound has potential application value in the field of medicine and material science. It can be used in the synthesis of chemicals and pharmaceutical intermediates, and also as a building block for organic light-emitting materials.
Preparation Method:
3-(4-bromophenyl)-6-methyl-2H-1,4-benzoxazine can be synthesized by a variety of methods. One commonly used method is the reaction of 4-bromoanisole with indole under basic conditions to yield the desired product.
Safety Information:
Because the hazard and toxicity of the compound have not been evaluated, appropriate protective measures should be taken when using or handling the compound. It is recommended to wear appropriate protective clothing, gloves and eye protection during operation to avoid contact with skin and inhalation. Be sure to operate under well-ventilated conditions to avoid inhaling vapors of the compound. Follow relevant safety procedures and comply with national and local regulations.
Last Update：2024-04-09 21:04:16
