351184-42-4 - Names and Identifiers
351184-42-4 - Physico-chemical Properties
Molecular Formula | C20H21NO3
|
Molar Mass | 323.39 |
Density | 1.260±0.06 g/cm3(Predicted) |
Boling Point | 510.7±43.0 °C(Predicted) |
pKa | 14.77±0.20(Predicted) |
Storage Condition | 2-8°C |
351184-42-4 - Upstream Downstream Industry
351184-42-4 - Introduction
N-FMOC-4-PIPERIDINOL(N-FMOC-4-piperidinol) is an organic compound whose molecular formula is C18H17NO3. The following is a description of its nature, use, formulation and safety information:
Nature:
N-FMOC-4-PIPERIDINOL is a white solid, soluble in some organic solvents such as chloroform and dimethylformamide. It has a lower melting point and a higher boiling point.
Use:
N-FMOC-4-PIPERIDINOL is a common reagent in organic synthesis. It is commonly used in the synthesis of piperidines in natural products and pharmaceuticals. It can control the structure and functionalization of the piperidine skeleton by hydroxyl protection and subsequent reaction.
Method:
N-FMOC-4-PIPERIDINOL can be synthesized by the reaction of piperidine and fluoroformate. First, piperidine is reacted with a fluoroformate under basic conditions to form an intermediate, which is then hydrolyzed under acidic conditions to give the final product.
Safety Information:
N-FMOC-4-PIPERIDINOL compounds need to be handled safely. It may be irritating, so appropriate personal protective measures should be taken during operation, such as wearing gloves, goggles and skin cream. At the same time, inhalation or contact with skin and eyes should be avoided. In case of accidental inhalation or contact, rinse immediately with plenty of water and seek medical help. During use or storage, it should be placed in a dry, well-ventilated place, away from ignition and flammable substances.
Last Update:2024-04-09 21:11:58