3512-12-7
4-bromo-3,5,6-trifluoropyridin-2-amine
CAS: 3512-12-7
Molecular Formula: C5H2BrF3N2
3512-12-7 - Names and Identifiers
| Name | 4-bromo-3,5,6-trifluoropyridin-2-amine |
| Synonyms | 4-bromo-3,5,6-trifluoropyridin-2-amine 2-Amino-4-bromo-3,5,6-trifluoropyridine 2-AMINO-4-BROMO-3,5,6-TRIFLUOROPYRIDINE 2-Pyridinamine, 4-bromo-3,5,6-trifluoro- |
| CAS | 3512-12-7 |
| InChI | InChI=1/C5H2BrF3N2/c6-1-2(7)4(9)11-5(10)3(1)8/h(H2,10,11) |
3512-12-7 - Physico-chemical Properties
| Molecular Formula | C5H2BrF3N2 |
| Molar Mass | 226.98 |
| Density | 1.995±0.06 g/cm3(Predicted) |
| Melting Point | 116-117 |
| Boling Point | 116-117 °C |
| Flash Point | 91.4°C |
| Vapor Presure | 0.0774mmHg at 25°C |
| pKa | -0.45±0.10(Predicted) |
| Refractive Index | 1.55 |
3512-12-7 - Risk and Safety
| Hazard Symbols | T - Toxic |
3512-12-7 - Introduction
4-bromo-3,5,6-trifluoropyridin-2-amine (4-bromo-3,5,6-trifluoropyridin-2-amine) is an organic compound. Its chemical formula is C5H2BrF3N and its molecular weight is 214.98g/mol.
Properties of the compound:
1. Appearance: colorless crystal or white to yellow solid.
2. Melting point: about 110-115°C.
3. Solubility: Soluble in organic solvents, insoluble in water.
Its main uses include:
1. pesticide intermediates: can be used as intermediates of pesticides to synthesize compounds with insecticidal activity.
2. drug research: can be used for the synthesis of lead compounds, and biological activity evaluation research.
Preparation method and synthetic route:
4-bromo-3,5,6-trifluoropyridin-2-amine can be prepared by the following synthetic route:
First, 4-bromo-3, 5,6-trifluoropyridine is used as a starting material, and an amino group is introduced by reacting with an amination reagent (such as ammonia water or butyl amine).
Reaction equation: C5H2BrF3N NH3 → C5H3BrF3N2
Finally, the desired product is obtained by crystallization or other purification methods.
Safety Information:
Because there is no special safety information, it is necessary to follow proper laboratory practices and use personal protective equipment to ensure safety when storing, handling and handling chemicals according to their characteristics. When using or handling the compound, follow local regulations and safe practices and avoid contact with skin, eyes and respiratory tract. In case of accident or inhalation or contact with the substance, seek medical attention immediately.
Properties of the compound:
1. Appearance: colorless crystal or white to yellow solid.
2. Melting point: about 110-115°C.
3. Solubility: Soluble in organic solvents, insoluble in water.
Its main uses include:
1. pesticide intermediates: can be used as intermediates of pesticides to synthesize compounds with insecticidal activity.
2. drug research: can be used for the synthesis of lead compounds, and biological activity evaluation research.
Preparation method and synthetic route:
4-bromo-3,5,6-trifluoropyridin-2-amine can be prepared by the following synthetic route:
First, 4-bromo-3, 5,6-trifluoropyridine is used as a starting material, and an amino group is introduced by reacting with an amination reagent (such as ammonia water or butyl amine).
Reaction equation: C5H2BrF3N NH3 → C5H3BrF3N2
Finally, the desired product is obtained by crystallization or other purification methods.
Safety Information:
Because there is no special safety information, it is necessary to follow proper laboratory practices and use personal protective equipment to ensure safety when storing, handling and handling chemicals according to their characteristics. When using or handling the compound, follow local regulations and safe practices and avoid contact with skin, eyes and respiratory tract. In case of accident or inhalation or contact with the substance, seek medical attention immediately.
Last Update：2024-04-09 21:04:16
