35674-27-2
4-Iodo-3-nitrobenzoic acid
CAS: 35674-27-2
Molecular Formula: C7H4INO4
35674-27-2 - Names and Identifiers
| Name | 4-Iodo-3-nitrobenzoic acid |
| Synonyms | 4-iodo-3-nitrobenzoicaci 4-Iodo-3-nitrobenzoic acid 4-IODO-3-NITROBENZOIC ACID 3-Nitro-4-iodobenzoic acid Benzoic acid, 4-iodo-3-nitro- |
| CAS | 35674-27-2 |
| EINECS | 670-347-6 |
| InChI | InChI=1/C7H4INO4/c8-5-2-1-4(7(10)11)3-6(5)9(12)13/h1-3H,(H,10,11) |
35674-27-2 - Physico-chemical Properties
| Molecular Formula | C7H4INO4 |
| Molar Mass | 293.02 |
| Density | 2.156±0.06 g/cm3(Predicted) |
| Melting Point | 208-211°C |
| Boling Point | 390.2±37.0 °C(Predicted) |
| Flash Point | 189.8°C |
| Water Solubility | Insoluble in water. |
| Vapor Presure | 8.66E-07mmHg at 25°C |
| pKa | 3.32±0.10(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Sensitive | Light Sensitive |
| Refractive Index | 1.702 |
35674-27-2 - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
35674-27-2 - Introduction
4-Iodo-3-nitrobenzoic acid is an organic compound with the chemical formula C7H4INO4. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 4-Iodo-3-nitrobenzoic acid is a yellow crystalline powder.
-Melting point: about 230°C.
-Solubility: Soluble in ethanol, ether and chloroform, insoluble in water.
Use:
- 4-Iodo-3-nitrobenzoic acid is mainly used as an intermediate in organic synthesis.
-It is an important raw material for the synthesis of drugs and pesticides.
-It can also be used for the synthesis of light emitting layers in organic electroluminescent devices (OLED).
Preparation Method:
There are many methods for the preparation of 4-Iodo-3-nitrobenzoic acid, one of which is commonly used to obtain by nitration of iodobenzoic acid. The specific preparation steps are as follows:
1. dissolve iodobenzoic acid in concentrated nitric acid.
2. Slowly add concentrated sulfuric acid at low temperature and stir the reaction.
3. After the reaction is carried out for a period of time, the product in the reaction solution is separated by filtration or crystallization.
4. 4-Iodo-3-nitrobenzoic acid was finally purified by washing with an appropriate solvent and crystallization.
Safety Information:
- 4-Iodo-3-nitrobenzoic acid is an organic compound. Personal protective measures should be taken when using it, such as wearing gloves and eye protection glasses.
-The compound is corrosive to a certain extent, avoid skin contact and inhalation.
-During the operation, pay attention to avoid contact with strong oxidants and reducing agents to avoid dangerous reactions.
-During storage, it should be stored in a cool, dry, well-ventilated place, separated from flammable substances and combustibles.
-If contact occurs, immediately rinse the affected area with plenty of water and seek medical help.
Nature:
-Appearance: 4-Iodo-3-nitrobenzoic acid is a yellow crystalline powder.
-Melting point: about 230°C.
-Solubility: Soluble in ethanol, ether and chloroform, insoluble in water.
Use:
- 4-Iodo-3-nitrobenzoic acid is mainly used as an intermediate in organic synthesis.
-It is an important raw material for the synthesis of drugs and pesticides.
-It can also be used for the synthesis of light emitting layers in organic electroluminescent devices (OLED).
Preparation Method:
There are many methods for the preparation of 4-Iodo-3-nitrobenzoic acid, one of which is commonly used to obtain by nitration of iodobenzoic acid. The specific preparation steps are as follows:
1. dissolve iodobenzoic acid in concentrated nitric acid.
2. Slowly add concentrated sulfuric acid at low temperature and stir the reaction.
3. After the reaction is carried out for a period of time, the product in the reaction solution is separated by filtration or crystallization.
4. 4-Iodo-3-nitrobenzoic acid was finally purified by washing with an appropriate solvent and crystallization.
Safety Information:
- 4-Iodo-3-nitrobenzoic acid is an organic compound. Personal protective measures should be taken when using it, such as wearing gloves and eye protection glasses.
-The compound is corrosive to a certain extent, avoid skin contact and inhalation.
-During the operation, pay attention to avoid contact with strong oxidants and reducing agents to avoid dangerous reactions.
-During storage, it should be stored in a cool, dry, well-ventilated place, separated from flammable substances and combustibles.
-If contact occurs, immediately rinse the affected area with plenty of water and seek medical help.
Last Update：2024-04-09 15:17:57
