35853-45-3

35853-45-3 - Names and Identifiers

Name	4-bromo-2,8-bis(trifluoromethyl)quinoline
Synonyms	2,8-BIS(TRIFL )-4-BROMOQUINOL 1-METHYL-3-(AMINOMETHYL)PIPERIDINE 2,8-BIS(TRIFLUOROMETHYL)-4-BROMOQUINOLIN 2,8-BIS(TRIFLUOROMETHYL)-4-BROMOQUINOLINE 4-BROMO-2,8-BIS(TRIFLUOROMETHYL)QUINOLINE 2,8-Bis(Trifluoromethyl)-4-Bromoquinoline 4-bromo-2,8-bis(trifluoromethyl)quinoline Quinoline, 4-bromo-2,8-bis(trifluoromethyl)-
CAS	35853-45-3
EINECS	609-183-7
InChI	InChI=1/C11H4BrF6N/c12-7-4-8(11(16,17)18)19-9-5(7)2-1-3-6(9)10(13,14)15/h1-4H

35853-45-3 - Physico-chemical Properties

Molecular Formula	C11H4BrF6N
Molar Mass	344.05
Density	1.720±0.06 g/cm3(Predicted)
Melting Point	62-64°C(lit.)
Boling Point	281.6±35.0 °C(Predicted)
Flash Point	124.1°C
Solubility	Chloroform (Slightly), Methanol (Slightly)
Vapor Presure	0.00603mmHg at 25°C
Appearance	Crystalline Powder
Color	Off-white to yellow
pKa	-3.67±0.50(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.51

35853-45-3 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3

35853-45-3 - Introduction

4-bromo-2,8-bis(trifluoromethyl)quinoline is an organic compound with the chemical formula C12H3BrF6N.

Nature:
-Appearance: colorless crystal
-melting point: 80-82 ℃
-Boiling point: 384 ℃
-Solubility: Dissolved in some organic solvents, such as ethanol, acetone, dichloromethane, etc.

Use:
4-bromo-2,8-bis(trifluoromethyl)quinoline is an important intermediate compound with a wide range of applications, including:
-Drug synthesis: It can be used to synthesize organic molecules with biological activity, such as drugs, pesticides, etc.
-Optoelectronic devices: can be used to prepare light-emitting diode (LED) materials.

Preparation Method:
The synthesis of 4-bromo-2,8-bis(trifluoromethyl)quinoline is usually carried out by the following steps:
1.2,8-bis(trifluoromethyl)quinoline reacts with sodium bromide in an organic solvent to generate 4-bromo-2,8-bis(trifluoromethyl)quinoline.

Safety Information:
4-bromo-2,8-bis(trifluoromethyl)quinoline is highly toxic to the environment, and protective measures should be taken. Avoid contact with oxidizing agents during use or storage. If taken by mistake or inhaled, seek medical attention immediately.

Last Update：2024-04-09 02:00:45