360-92-9
N,N-diethyl-2,2,2-trifluoroacetamide
CAS: 360-92-9
Molecular Formula: C6H10F3NO
360-92-9 - Names and Identifiers
| Name | N,N-diethyl-2,2,2-trifluoroacetamide |
| Synonyms | N,N-DIETHYLTRIFLUOROACETAMIDE N,N-DIETHYL-2,2,2-TRIFLUOROACETAMIDE N,N-diethyl-2,2,2-trifluoroacetamide Acetamide, N,N-diethyl-2,2,2-trifluoro- |
| CAS | 360-92-9 |
| InChI | InChI=1/C6H10F3NO/c1-3-10(4-2)5(11)6(7,8)9/h3-4H2,1-2H3 |
360-92-9 - Physico-chemical Properties
| Molecular Formula | C6H10F3NO |
| Molar Mass | 169.14 |
| Density | 1.2g/mLat 25°C(lit.) |
| Boling Point | 65-67°C24mm Hg(lit.) |
| Flash Point | 110°F |
| Vapor Presure | 0.83mmHg at 25°C |
| Appearance | clear liquid |
| Specific Gravity | 1.200 |
| Color | Colorless to Light yellow to Light orange |
| Refractive Index | n20/D 1.38(lit.) |
360-92-9 - Risk and Safety
| Risk Codes | R10 - Flammable R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| UN IDs | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| Hazard Class | 3 |
| Packing Group | III |
360-92-9 - Introduction
N,N-diethyl-2,2,2-trifluoroacetamide is an organic compound with the chemical formula C6H10F3NO. It is a colorless liquid with a strong odor at room temperature.
N,N-diethyl-2,2,2-trifluoroacetamide is commonly used in amine protection, amide protection and fluorination reactions in organic synthesis. It can be used as a reagent or solvent, for example, as a ligand for transition metal catalysts and organic catalysts in fluorination reactions.
The method for preparing N,N-diethyl-2,2,2-trifluoroacetamide is usually obtained by reacting 2,2, 2-trifluoroacetic acid with diethylamine. Specific steps can refer to the relevant synthetic route in the organic synthesis manual.
When using and storing N,N-diethyl-2,2,2-trifluoroacetamide, you need to pay attention to its safety. It is irritating to the eyes and skin and may cause damage to the respiratory system. Therefore, appropriate protective equipment such as safety glasses, gloves and respiratory protection should be worn during operation.
In addition, N,N-diethyl-2,2,2-trifluoroacetamide is a flammable liquid and should avoid contact with fire sources. Storage should be kept in a cool, ventilated and dry place, away from fire and oxidant.
N,N-diethyl-2,2,2-trifluoroacetamide is commonly used in amine protection, amide protection and fluorination reactions in organic synthesis. It can be used as a reagent or solvent, for example, as a ligand for transition metal catalysts and organic catalysts in fluorination reactions.
The method for preparing N,N-diethyl-2,2,2-trifluoroacetamide is usually obtained by reacting 2,2, 2-trifluoroacetic acid with diethylamine. Specific steps can refer to the relevant synthetic route in the organic synthesis manual.
When using and storing N,N-diethyl-2,2,2-trifluoroacetamide, you need to pay attention to its safety. It is irritating to the eyes and skin and may cause damage to the respiratory system. Therefore, appropriate protective equipment such as safety glasses, gloves and respiratory protection should be worn during operation.
In addition, N,N-diethyl-2,2,2-trifluoroacetamide is a flammable liquid and should avoid contact with fire sources. Storage should be kept in a cool, ventilated and dry place, away from fire and oxidant.
Last Update：2024-04-10 22:29:15
