3743-28-0
3-Hydroxybenzanilide
CAS: 3743-28-0
Molecular Formula: C13H11NO2
3743-28-0 - Names and Identifiers
| Name | 3-Hydroxybenzanilide |
| Synonyms | M-HYDROXYBENZANILIDE 3-Hydroxybenzanilide 3-HYDROXYBENZANILIDE N-(3-hydroxyphenyl)benzamide Benzamide, N-(3-hydroxyphenyl)- |
| CAS | 3743-28-0 |
3743-28-0 - Physico-chemical Properties
| Molecular Formula | C13H11NO2 |
| Molar Mass | 213.23 |
| Density | 1.278±0.06 g/cm3(Predicted) |
| Melting Point | 153 °C |
| Boling Point | 300.1±25.0 °C(Predicted) |
| pKa | 9.57±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD00068823 |
3743-28-0 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
3743-28-0 - Introduction
3-Hydroxybenzanilide, also known as 3-hydroxyphenylbenzamide, is an organic compound. The following describes its nature, use, preparation and safety information:
Nature:
-Appearance: 3-Hydroxybenzanilide is a white crystalline solid.
-Solubility: It dissolves well in common organic solvents and has relatively low solubility in water.
-Melting point: about 126-128°C.
Use:
3-Hydroxybenzanilide has a range of applications in the chemical and pharmaceutical fields:
-Chemical reagent: It can be used as a starting material or intermediate in organic synthesis.
-Optical material: It has specific optical properties and can be used in the optical field.
-Drugs: Some related compounds have antibacterial or antiviral activity, so they may be used in drug development.
Preparation Method:
The preparation method of 3-Hydroxybenzanilide can be carried out by the following steps:
1. reacting aniline with p-hydroxybenzoic acid in an appropriate solvent to obtain 3-hydroxyphenylbenzoic acid.
2. 3-hydroxyphenylbenzoic acid is reacted with an appropriate activating agent (e. g., DCC or EDC) to form its amide.
3. 3-Hydroxybenzanilide is obtained by crystallization purification or other methods.
Safety Information:
3-Hydroxybenzanilide is a chemical substance and should comply with the following safety measures:
-Avoid contact with skin, eyes and mucous membranes.
-Wear appropriate protective gloves, glasses and a protective mask when using.
-Avoid inhaling its powder or vapor, and operate in a well-ventilated place.
-Avoid contacting it with oxidants or combustible substances to avoid fire or explosion.
-In use and storage, please strictly follow the chemical safety procedures.
Nature:
-Appearance: 3-Hydroxybenzanilide is a white crystalline solid.
-Solubility: It dissolves well in common organic solvents and has relatively low solubility in water.
-Melting point: about 126-128°C.
Use:
3-Hydroxybenzanilide has a range of applications in the chemical and pharmaceutical fields:
-Chemical reagent: It can be used as a starting material or intermediate in organic synthesis.
-Optical material: It has specific optical properties and can be used in the optical field.
-Drugs: Some related compounds have antibacterial or antiviral activity, so they may be used in drug development.
Preparation Method:
The preparation method of 3-Hydroxybenzanilide can be carried out by the following steps:
1. reacting aniline with p-hydroxybenzoic acid in an appropriate solvent to obtain 3-hydroxyphenylbenzoic acid.
2. 3-hydroxyphenylbenzoic acid is reacted with an appropriate activating agent (e. g., DCC or EDC) to form its amide.
3. 3-Hydroxybenzanilide is obtained by crystallization purification or other methods.
Safety Information:
3-Hydroxybenzanilide is a chemical substance and should comply with the following safety measures:
-Avoid contact with skin, eyes and mucous membranes.
-Wear appropriate protective gloves, glasses and a protective mask when using.
-Avoid inhaling its powder or vapor, and operate in a well-ventilated place.
-Avoid contacting it with oxidants or combustible substances to avoid fire or explosion.
-In use and storage, please strictly follow the chemical safety procedures.
Last Update：2024-04-09 02:00:58
