374537-99-2
7-Amino-5-bromoindole
CAS: 374537-99-2
Molecular Formula: C8H7BrN2
374537-99-2 - Names and Identifiers
| Name | 7-Amino-5-bromoindole |
| Synonyms | 5-Bromo-7-indolamine 5-BROMO-7-INDOLAMINE 7-AMINO-5-BROMOINDOLE 7-Amino-5-bromoindole 5-BROMO-1H-INDOL-7-AMINE 5-bromo-1H-indol-7-amine |
| CAS | 374537-99-2 |
| InChI | InChI=1/C8H7BrN2/c9-6-3-5-1-2-11-8(5)7(10)4-6/h1-4,11H,10H2 |
374537-99-2 - Physico-chemical Properties
| Molecular Formula | C8H7BrN2 |
| Molar Mass | 211.06 |
| Density | 1.753g/cm3 |
| Melting Point | 104-105°C |
| Boling Point | 405.6°C at 760 mmHg |
| Flash Point | 199.1°C |
| Vapor Presure | 8.68E-07mmHg at 25°C |
| Storage Condition | 2-8°C(protect from light) |
| Sensitive | Air Sensitive |
| Refractive Index | 1.779 |
| MDL | MFCD02093961 |
374537-99-2 - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R25 - Toxic if swallowed |
| Safety Description | S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN2811 |
| Hazard Class | 6.1 |
| Packing Group | III |
374537-99-2 - Introduction
7-Amino-5-bromoindole(7-Amino-5-bromoindole) is an organic compound with the chemical formula C8H6BrN. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 7-Amino-5-bromoindole is a colorless to pale yellow crystalline powder.
-Solubility: It dissolves in organic solvents such as chloroform, diethyl ether and dimethyl sulfoxide, but is hardly soluble in water.
Use:
-Chemical research: 7-Amino-5-bromoindole is often used as a chemical reagent in the field of organic synthesis and pharmaceutical research.
-Drugs: It may have some activity against cancer cells and can be used to develop anti-tumor drugs.
Preparation Method:
7-Amino-5-bromoindole can be synthesized by the following steps:
1.5-bromoindole is reacted with ammonium chloride to obtain 5-bromoindole ketone.
2.5-bromo -1-nitroindole is converted to 5-bromo -1-nitroindole by nitrosylation reaction.
3. 5-bromo-1-nitroindole is reacted with sodium sulfite to give 7-Amino-5-bromoindole.
Safety Information:
- 7-Amino-5-bromoindole is a chemical that needs to be handled under suitable laboratory conditions.
-Pay attention to personal protective measures when using, such as wearing gloves, goggles and protective clothing.
-Avoid inhalation, ingestion or skin contact, avoid contact with eyes and mucous membranes.
-In the event of accidental exposure or ingestion, seek prompt medical assistance and carry a safety data sheet for this compound.
Nature:
-Appearance: 7-Amino-5-bromoindole is a colorless to pale yellow crystalline powder.
-Solubility: It dissolves in organic solvents such as chloroform, diethyl ether and dimethyl sulfoxide, but is hardly soluble in water.
Use:
-Chemical research: 7-Amino-5-bromoindole is often used as a chemical reagent in the field of organic synthesis and pharmaceutical research.
-Drugs: It may have some activity against cancer cells and can be used to develop anti-tumor drugs.
Preparation Method:
7-Amino-5-bromoindole can be synthesized by the following steps:
1.5-bromoindole is reacted with ammonium chloride to obtain 5-bromoindole ketone.
2.5-bromo -1-nitroindole is converted to 5-bromo -1-nitroindole by nitrosylation reaction.
3. 5-bromo-1-nitroindole is reacted with sodium sulfite to give 7-Amino-5-bromoindole.
Safety Information:
- 7-Amino-5-bromoindole is a chemical that needs to be handled under suitable laboratory conditions.
-Pay attention to personal protective measures when using, such as wearing gloves, goggles and protective clothing.
-Avoid inhalation, ingestion or skin contact, avoid contact with eyes and mucous membranes.
-In the event of accidental exposure or ingestion, seek prompt medical assistance and carry a safety data sheet for this compound.
Last Update：2024-04-09 15:17:57
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CAS: 374537-99-2
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CAS: 374537-99-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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