37517-30-9
Acebutolol
CAS: 37517-30-9
Molecular Formula: C18H28N2O4
37517-30-9 - Names and Identifiers
| Name | Acebutolol |
| Synonyms | Acebutolol dl-Acebutolol 3'-Acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide 5'-Butyramido-2'-(2-hydroxy-3-isopropylaminopropoxy)acetophenone 1-(2-Acetyl-4-n-butyramidophenoxy)-2-hydroxy-3-isopropylaminopropane |
| CAS | 37517-30-9 |
| EINECS | 253-539-0 |
37517-30-9 - Physico-chemical Properties
| Molecular Formula | C18H28N2O4 |
| Molar Mass | 336.43 |
| Density | 1.1748 (rough estimate) |
| Melting Point | 119-123°C |
| Boling Point | 472.9°C (rough estimate) |
| Water Solubility | 259 mg/L |
| Color | Crystals |
| pKa | pKa 9.40 (Uncertain) |
| Storage Condition | -20°C Freezer |
| Refractive Index | 1.5700 (estimate) |
| Physical and Chemical Properties | Crystals, melting point 119~123 ℃. Its hydrochloride [34381-68-5] has a melting point of 141~143 ℃. |
37517-30-9 - Risk and Safety
| Toxicity | TDLo orl-wmn: 152 mg/kg:CVS,BPR JTCTDW 20,69,83 |
37517-30-9 - References
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Overview | acebutolol (Ac) is a beta-adrenoceptor blocker used to treat hypertension, arrhythmia, or angina. The drug was approved by the U. S. FDA in 1999, and like many other beta-blocker drugs, the drug is still administered in a mixed manner. |
| Use | cardiovascular β-blockers. |
| production method | from 5 '-butanamide -2'-(2, 3-epoxypropoxy) acetophenone, isopropylamine was obtained by reaction. |
| category | toxic substances |
| toxicity grade | poisoning |
| Acute toxicity | intravenous-canine LD50:4 mg/kg |
| flammability hazard characteristics | flammability; Heat decomposition releases toxic nitric oxide smoke; Drug side effects: cardiovascular and respiratory system abnormalities, abnormal bone growth |
| storage and transportation characteristics | warehouse ventilation and low temperature drying |
| extinguishing agent | dry powder, foam, sand and water |
Last Update：2024-04-09 15:17:17
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Product Name: Acebutolol Monomer Request for quotation
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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