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376608-71-8

(1R,2R)-2-(3,4-difluorophenyl) cyclopropanamine(S)-(carboxylato(phenyl) methyl)holmium

CAS: 376608-71-8

Molecular Formula: C17H17F2NO3

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376608-71-8 - Names and Identifiers

Name (1R,2R)-2-(3,4-difluorophenyl) cyclopropanamine(S)-(carboxylato(phenyl) methyl)holmium
Synonyms Ticagrelor InterMediate 4
trans-(1R,2S)-2-(2,3-difluorophenyl)cyclopropylaMine Mandelat
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaMine (2R)-Hydroxy(phenyl)ethanoate
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium 2R)-hydroxy(phenyl)ethanoate
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium(2R)-hydroxy(phenyl)ethanoate
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium (2R)-hydroxy(phenyl)ethanoate
(1R,2R)-2-(3,4-difluorophenyl)cyclopropanamine(S)-(carboxylato(phenyl)methyl)holmium
(1R,2R)-2-(3,4-difluorophenyl) cyclopropanamine(S)-(carboxylato(phenyl) methyl)holmium
(αR)-α-Hydroxybenzeneacetic Acid coMpd. with (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaMine
(alphaR)-alpha-Hydroxybenzeneacetic acid compd. with (1R,2S)-2-(3,4-difluorophenyl)cyclopropanamine
CAS 376608-71-8
EINECS 1308068-626-2

376608-71-8 - Physico-chemical Properties

Molecular FormulaC17H17F2NO3
Molar Mass321.32
Storage Conditionunder inert gas (nitrogen or Argon) at 2–8 °C

376608-71-8 - Risk and Safety

Safety Description24/25 - Avoid contact with skin and eyes.
HS Code29181990

376608-71-8 - Reference Information

overview (1R,2S)-2-(3, 4-difluorophenyl) cyclopropylamine (R)-mandelate is a light yellow to white powder and can be used as a pharmaceutical intermediate.
Use (1R,2S)-2-(3, 4-difluorophenyl) cyclopropylamine (R)-mandelate is an intermediate for preparing orally active reversible P2Y12 receptor antagonists (such as Ticagrelor(T437700)) to prevent thrombosis.
application (1R,2S)-2-(3, 4-difluorophenyl) cyclopropylamine (R)-mandelate is a carboxylic acid derivative, which can be used as an intermediate of the anticoagulant drug ticagrelor.
preparation stereoselective synthesis of (1R,2R)-2-(3, 4-difluorophenyl) cyclopropylnitrile II through the cyclopropanylation reaction of camphor matium ylide I and acrylonitrile, and then through hydrolysis and holfman degradation reaction to obtain the target product, (1R,2S)-2-(3, 4-Difluorophenyl) cyclopropylamine (R)-mandelate.
Last Update：2024-04-09 20:02:46
376608-71-8
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CAS: 376608-71-8
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Email: 2853786052@qq.com
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QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: (1R,2R)-2-(3,4-difluorophenyl) cyclopropanamine(S)-(carboxylato(phenyl) methyl)holmium Request for quotation
CAS: 376608-71-8
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: (1R,2R)-2-(3,4-difluorophenyl) cyclopropanamine(S)-(carboxylato(phenyl) methyl)holmium Request for quotation
CAS: 376608-71-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium (2R)-hydroxy(phenyl)ethanoate Visit Supplier Webpage Request for quotation
CAS: 376608-71-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
Chem-stone
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CAS: 376608-71-8
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376608-71-8
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