3780-41-4

3780-41-4 - Names and Identifiers

Name	3-methyl-1H-pyrrole-2,4-dicarboxylic acid
Synonyms	3-Methyl-pyrrole-2,4-dicarboxylic acid 3-methyl-1H-pyrrole-2,4-dicarboxylic acid 3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 1H-Pyrrole-2,4-dicarboxylic acid, 3-methyl-
CAS	3780-41-4
InChI	InChI=1/C7H7NO4/c1-3-4(6(9)10)2-8-5(3)7(11)12/h2,8H,1H3,(H,9,10)(H,11,12)

3780-41-4 - Physico-chemical Properties

Molecular Formula	C7H7NO4
Molar Mass	169.13
Density	1.550±0.06 g/cm3(Predicted)
Melting Point	>300℃
Boling Point	482.1±45.0 °C(Predicted)
Flash Point	245.4°C
Vapor Presure	4.18E-10mmHg at 25°C
pKa	4.51±0.50(Predicted)
Storage Condition	2-8°C
Refractive Index	1.641

3780-41-4 - Introduction

3-methyl-1H-pyrrole-2,4-dicarboxylic acid is an organic compound with the chemical formula C7H7NO4. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 3-methyl-1H-pyrrole-2,4-dicarboxylic acid is a white to pale yellow solid.
-Melting point: about 165-170°C.
-Solubility: 3-methyl-1H-pyrrole-2,4-dicarboxylic acid is insoluble in water and has good solubility in organic solvents (such as ethanol, chloroform, dimethyl sulfoxide, etc.).

Use:
- 3-methyl-1H-pyrrole-2,4-dicarboxylic acid is often used as an important intermediate in organic synthesis and medicinal chemistry.
-It can be used to synthesize pyrrole compounds, drugs and dyes.

Preparation Method:
The preparation method of 3-methyll-1H-chrrole-2, 4-dicarboxylic acid is as follows:
1. First, the corresponding methylene compound is obtained by ketonization reaction of pyrrole through N-propylpyrrole-2-carboxylate.
2. Then, the methylene compound is subjected to an ester hydrolysis reaction to generate 3-methyl-1H-pyrrole-2,4-dicarboxylic acid.

Safety Information:
- 3-methyl-1H-pyrrole-2,4-dicarboxylic acid has no obvious acute toxicity under normal conditions.
-However, if it is necessary to handle the compound, please follow appropriate laboratory procedures and wear appropriate personal protective equipment, such as laboratory gloves and goggles.
-Any further safety information related to the use of this compound should refer to the relevant safety data sheet or consult a professional.

Last Update：2024-04-09 21:01:54