380430-61-5

380430-61-5 - Names and Identifiers

Name	(2-Acetylaminophenyl)boronic acid, pinacol ester
Synonyms	2-ACETAMIDOPHENYLBORONIC ACID, PINACOL ESTER 2-Acetylaminophenylboronic acid pinacol ester 2-ACETAMIDOBENZENEBORONIC ACID, PINACOL ESTER 2-ACETYLAMINOPHENYLBORONIC ACID, PINACOL ESTER (2-Acetylaminophenyl)boronic acid, pinacol ester 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ACETANILIDE N-[2-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide 2'-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ACETANILIDE N-(2-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetaMide N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)
CAS	380430-61-5
InChI	InChI=1/C14H20BNO3/c1-10(17)16-12-9-7-6-8-11(12)15-18-13(2,3)14(4,5)19-15/h6-9H,1-5H3,(H,16,17)

380430-61-5 - Physico-chemical Properties

Molecular Formula	C14H20BNO3
Molar Mass	261.12
Density	1.07±0.1 g/cm3(Predicted)
Melting Point	172-176°C(lit.)
Boling Point	424.2±28.0 °C(Predicted)
Flash Point	210.3°C
Vapor Presure	2.11E-07mmHg at 25°C
pKa	15.26±0.70(Predicted)
Storage Condition	2-8°C
Refractive Index	1.51
Physical and Chemical Properties	Melting point 172-176°C

380430-61-5 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany	3
Hazard Note	Irritant

380430-61-5 - Introduction

(2-Acetylaminophenyl)boronic acid, pinacol ester is an organic compound whose chemical formula is C14H19BNO3. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Common form is white to light yellow crystal
-Solubility: Soluble in some organic solvents (such as dimethylformamide, dichloromethane), but poor solubility in water.

Use:
- (2-Acetylaminophenyl)boronic acid, pinacol ester can be used as an intermediate in organic synthesis. It is an important raw material for the preparation of other organic compounds, especially for the synthesis of drugs or drug candidate compounds in the pharmaceutical field.
-It is widely used in the field of medicine, especially in the research of designing new drugs. It is used in drug discovery and development to synthesize biologically active molecules, such as anticancer drugs, kinase inhibitors, etc.

Preparation Method:
- (2-Acetylaminophenyl)boronic acid, the synthesis of pinacol ester is usually realized by reacting phenylboronic acid and 2-acetanilide. First, phenylboronic acid and 2-acetanilide are reacted in an appropriate solvent, and then pinacol (pinacol) is added under appropriate conditions to make it undergo esterification reaction to form (2-Acetylaminophenyl)boronic acid, pinacol ester.

Safety Information:
- (2-Acetylaminophenyl)boronic acid, pinacol the specific safety information of ester will vary according to different manufacturers and suppliers, so you should carefully read the relevant safety technical instructions (MSDS) before use.
-Generally speaking, it should be stored in a dry, cool, well-ventilated place, and avoid contact with oxidants and strong acids and alkalis. During the operation, appropriate personal protective equipment, such as chemical protective clothing, gloves and goggles, is required.

Last Update：2024-04-09 21:01:54