ethyl 4-amino-6-chloronicotinate is an organic compound with the chemical formula C8H8ClNO2. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: ethyl 4-amino-6-choronicotinate is a colorless or slightly yellow crystalline solid.
-Solubility: Its solubility in water is lower, and it is easier to dissolve in organic solvents such as ethanol and dimethylformamide (DMF).
-Melting point: Its melting point range is approximately 135-137 ° C.
Use:
-Drug synthesis: ethyl 4-amino-6-choronicotinate is widely used as an intermediate in the field of drug synthesis, and is used to synthesize some biologically active compounds, such as antibiotics, anti-cancer drugs and anti-inflammatory drugs.
Method:
- ethyl 4-amino-6-chloronicotinate can be formed by reacting chloronicotinate with ethanol and ammonia. Specific synthetic methods can be found in the Handbook of organic synthesis.
Safety Information:
- ethyl 4-amino-6-choronicotinate needs to pay attention to safety measures during use and storage to prevent inhalation, intake or skin contact.
-It may be irritating to the eyes, skin and respiratory tract, so it is necessary to wear appropriate protective equipment such as chemical goggles, gloves and protective masks when handling.
-During use and storage, keep it away from fire sources and flammable substances, and keep the storage container sealed and placed in a cool, dry place.
Please note: When using any chemical substance, you must follow the correct laboratory procedures and take appropriate safety measures based on the detailed information provided in the chemical safety data sheet (MSDS).