38396-39-3
()-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
CAS: 2180-92-9;38396-39-3
Molecular Formula: C18H28N2O
38396-39-3 - Names and Identifiers
38396-39-3 - Physico-chemical Properties
| Molecular Formula | C18H28N2O |
| Molar Mass | 288.43 |
| Density | 1.032±0.06 g/cm3(Predicted) |
| Melting Point | 106-110℃ |
| Boling Point | 423.4±45.0 °C(Predicted) |
| Water Solubility | Soluble in water, ethanol, chloroform (slightly ), and acetone (slightly ). |
| pKa | 14.85±0.70(Predicted) |
38396-39-3 - Risk and Safety
| TSCA | Yes |
| Hazard Class | 6.1 |
38396-39-3 - Preparation Method
Open Data Verified Data
preparation of levobupivacaine each: racemic bupivacaine and L_() tartaric acid dissolved in acetone, stirred at room temperature until the solid is fully soluble, stir until complete precipitation of dexbupivacaine tartrate. The solid was filtered off, levobupivacaine tartrate was added to the filtrate, and the precipitate of levobupivacaine tartrate was precipitated with stirring. The solid was filtered off, racemic Bupivacaine was added to the filtrate, acetone was added, and the solid was stirred until complete. Seeds of dexbupivacaine tartrate were added and stirred for about 7h, and this continued. Dexbupivacaine tartrate and levobupivacaine tartrate were obtained each time. Levobupivacaine tartrate was dissolved in water with stirring and the pH was adjusted with concentrated aqueous ammonia. The crude levobupivacaine was obtained by filtration, washing with water, drying to constant weight, and recrystallized from hot isopropanol to obtain pure levobupivacaine.
Last Update：2024-01-02 23:10:35
38396-39-3 - Use
Open Data Verified Data
Cellech Chiroscience, UK, was first launched in the United States in March 2000. Levobupivacaine is a single isomer of bupivacaine, with better safety and less central nervous system and cardiac toxicity than bupivacaine. For surgical and obstetric local or regional anesthesia, as well as postoperative pain control.
Last Update：2022-01-01 09:09:25
38396-39-3 - Safety
Open Data Verified Data
Mice (bupivacaine hydrochloride) intravenous injection, subcutaneous injection of LDsa (mg/kg):7.8.82.
Last Update：2022-01-01 09:09:25
38396-39-3 - Introduction
(+)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide is a local anesthetic with local anesthetic effect. The following is an introduction to the nature, use, preparation and safety information of ()-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide:
Nature:
()-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide is a colorless crystalline powder, soluble in water. It is a kind of amide local anesthetic drugs, with good anesthetic effect and lasting action time.
Use:
()-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide is mainly used for local anesthesia, and is often used for surface anesthesia of skin and mucous membranes, as well as low-concentration local infiltration anesthesia. It can be used for surgical procedures, pain treatment and for various medical examinations.
Preparation Method:
The preparation method of ()-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide is mainly obtained by the reaction of p-methylphenylhydrazine and p-nitroaniline. The specific process may vary industrially, but generally involves the steps of acylation and reduction of the substrate.
Safety Information:
()-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide is relatively safe when used correctly, but there are some potential risks. Overdose, injection into blood vessels, or allergic reactions may cause side effects such as dizziness, nausea, vomiting, and allergies. Should follow the doctor's advice and the correct dosage, avoid the use of expired drugs. In the course of use, should pay attention to observe the patient's reaction, and immediately seek medical treatment to deal with any abnormal symptoms.
Nature:
()-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide is a colorless crystalline powder, soluble in water. It is a kind of amide local anesthetic drugs, with good anesthetic effect and lasting action time.
Use:
()-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide is mainly used for local anesthesia, and is often used for surface anesthesia of skin and mucous membranes, as well as low-concentration local infiltration anesthesia. It can be used for surgical procedures, pain treatment and for various medical examinations.
Preparation Method:
The preparation method of ()-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide is mainly obtained by the reaction of p-methylphenylhydrazine and p-nitroaniline. The specific process may vary industrially, but generally involves the steps of acylation and reduction of the substrate.
Safety Information:
()-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide is relatively safe when used correctly, but there are some potential risks. Overdose, injection into blood vessels, or allergic reactions may cause side effects such as dizziness, nausea, vomiting, and allergies. Should follow the doctor's advice and the correct dosage, avoid the use of expired drugs. In the course of use, should pay attention to observe the patient's reaction, and immediately seek medical treatment to deal with any abnormal symptoms.
Last Update：2024-04-09 19:05:00
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Email: 2853786052@qq.com
Mobile: 86+15671228036
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Wechat: 15671228036
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Product Name: Bupivacaine CAS 2180-92-9 Request for quotationCAS: 2180-92-9
Tel:
Email: Anna@weierchemical.com
WhatsApp: +8618532131551
Product Name: ()-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Request for quotation
CAS: 2180-92-9
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 2180-92-9
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
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