3a,4,7,7a-tetrahydro-2-(1,1,2,2-tetrachloroethyl)thio-1h-isoindole-1,3(2h)-dio
captafol
CAS: 2425-06-1
Molecular Formula: C10H9Cl4NO2S
3a,4,7,7a-tetrahydro-2-(1,1,2,2-tetrachloroethyl)thio-1h-isoindole-1,3(2h)-dio - Names and Identifiers
3a,4,7,7a-tetrahydro-2-(1,1,2,2-tetrachloroethyl)thio-1h-isoindole-1,3(2h)-dio - Physico-chemical Properties
| Molecular Formula | C10H9Cl4NO2S |
| Molar Mass | 349.06 |
| Density | 1.4682 (rough estimate) |
| Melting Point | 160-161° |
| Boling Point | 365.7±52.0 °C(Predicted) |
| Flash Point | >100°C |
| Water Solubility | 1.4 mg l-1 (20 °C) |
| Vapor Presure | 1.1 x 10-6 Pa (20 °C) |
| Merck | 13,1777 |
| pKa | -2.67±0.20(Predicted) |
| Storage Condition | 0-6°C |
| Refractive Index | 1.6000 (estimate) |
| Physical and Chemical Properties | Yellowish brown to white-like powder |
3a,4,7,7a-tetrahydro-2-(1,1,2,2-tetrachloroethyl)thio-1h-isoindole-1,3(2h)-dio - Risk and Safety
| Risk Codes | R45 - May cause cancer R43 - May cause sensitization by skin contact R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S53 - Avoid exposure - obtain special instructions before use. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN3077 9/PG 3 |
| RTECS | GW4900000 |
| HS Code | 29305000 |
| Toxicity | LD50 in rats, rabbits (mg/kg): 2500-6200 orally; 15400 dermally (Ben-Dyke) |
3a,4,7,7a-tetrahydro-2-(1,1,2,2-tetrachloroethyl)thio-1h-isoindole-1,3(2h)-dio - Reference Information
| agricultural fungicide | dikongdan is a white crystalline solid with a melting point of 160~161 ℃ and hardly volatilized at room temperature. Insoluble in water, slightly soluble in most organic solvents. It decomposes slowly at the melting point temperature. It is unstable under strong alkali conditions. Industrial products are bright yellow-brown powder with special smell. Dijundan is a non-systemic, protective agricultural fungicide used for foliar spraying. In 1961, it was produced by the Chevron Chemical Company of the United States (Chevron Chemical Company). It can prevent downy mildew, blight, anthracnose, etc. on a variety of crops, and has teratogenic effects. Toxicity LD505000 ~ 6200 mg/kg (oral to rats). The United States stipulates that the maximum allowable concentration in the air in the working environment is 0.1mg/m3. The Japanese pesticide residue standard stipulates that the maximum allowable concentration in apples is 5.0 mg/kg, and that in cabbage and radish (leaves and roots) is 1.0 mg/kg. [Precautions] 1. Do not mix with alkaline drugs and oil substances. 2. Dijundan is a low-toxic fungicide, but the dispensing and application personnel still need to pay attention to safety to prevent the liquid medicine from being inhaled or contaminated with the skin, and rinse in time after spraying. 3. Some people have allergic reactions to this fungicide and will get rash. Attention should be paid to protection. 4. After application, all kinds of tools should be cleaned, sewage and remaining liquid medicine should be properly treated and preserved, and should not be dumped arbitrarily, so as not to pollute fish ponds, water sources and soil. 5. Special vehicles and warehouses shall be provided for transportation and storage, and shall not be transported together with food and daily necessities. | |
| preparation method | tetrahydrophthalic anhydride is prepared from butadiene and maleic anhydride, and then ammonia and tetrahydrophthalic anhydride are reacted to form imine, and imine is then prepared by reacting with 1,1,2,2, 2-tetrachloroethyl sulfur chloride. Fig. 1 shows the synthetic route | |
| mode of action | dixidan is a broad-spectrum protective fungicide with multiple action points. The dimethylimide group (-CON(H)co-) in the structure has high bactericidal activity, which can control root rot, blight, downy mildew, blight and anthracnose of fruit trees, vegetables and cash crops, but has poor effect on powdery mildew. In addition to spraying, it can also be used for soil disinfection and seed treatment. | |
| toxicity | acute oral LD50 in rats is 5,000~6,200mg/kg, administered with water suspension of 80% wettable powder, and acute oral LD50 in rats is 2500mg/kg. Acute transdermal toxicity LD50>15400mg/ kg in rabbits. Daily use of 500mg/kg to rats or at a dose of 10mg/kg to dogs did not produce poisoning after two years of feeding experiments, but some people are allergic to Dijun Dan and have been proved to have carcinogenic effects. The LD50 for 10-day rearing of wild ducks and domestic ducks were> 23070mg/kg and 101700mg/kg, respectively. After 4 days of contact with rainbow trout, the half lethal concentration LC50 was 0.5 mg/L, goldfish was 3.0mg/L, green gill was 0.15mg/L, and big Mola was 2.8 mg/L. | |
| control object | is a protective fungicide, which has been widely used to control diseases of tomato leaves and fruits, potato wilt, coffee kernel fruit disease, and other agricultural, garden and forest crops. Can be used as wood preservative. The agricultural fungicide, preparation method, mode of action, toxicity, etc. of Dijongdan are edited by Yulian. (2016-03-04) | |
| dosage form | 80% dixindan wettable powder (Difolatan). | |
| chemical properties | yellowish brown to white powder | |
| category | pesticide | |
| toxicity classification | poisoning | |
| acute toxicity | oral-rat LD50: 2500 mg/kg; abdominal cavity-mouse LDL0: 3 mg/kg | |
| flammability hazard characteristics | combustion produces toxic chlorides, nitrogen oxides and phosphorus oxide gases | |
| storage and transportation characteristics | warehouse ventilation and low temperature drying; Separate storage and transportation from food raw materials | |
| extinguishing agent | dry powder, foam, sand | |
| occupational standard | TWA 0.1 mg/m3 | |
| (IARC) carcinogen classification | 2A (Vol. 53) 1991 | |
| EPA chemical information | The information is provided by: ofmpub.epa.gov (external link) | |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov provided (external link) |
Last Update：2024-04-10 22:29:15
Supplier List
Spot supply
Product Name: Captafol Visit Supplier Webpage Request for quotationCAS: 2425-06-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Captafol Visit Supplier Webpage Request for quotationCAS: 2425-06-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
View History