4(1H)-Pyrimidinethione

4(1H)-Pyrimidinethione - Names and Identifiers

Name	4(1H)-Pyrimidinethione (9CI)
Synonyms	PyriMidine-4-thiol 4-mercaptopyrimidine 4(3H)-Pyrimidinethione 4(1H)-Pyrimidinethione 4(1H)-Pyrimidinethione (9CI) 1,4-dihydropyrimidine-4-thione
CAS	1450-86-8

4(1H)-Pyrimidinethione - Physico-chemical Properties

Molecular Formula	C4H4N2S
Molar Mass	112.15
Density	1.30±0.1 g/cm3(Predicted)
Melting Point	190-192 °C(Solv: water (7732-18-5))
Boling Point	191.3±23.0 °C(Predicted)
pKa	6.90±0.10(Predicted)
Storage Condition	2-8°C

4(1H)-Pyrimidinethione - Introduction

4(1H)-Pyrimidinethione (9CI), also known as 4-mercaptopyrazine, is an organic compound. Its chemical formula is C4H4N2S, and its structure contains a sulfur atom and a nitrogen atom.

Nature:
1. Appearance: 4(1H)-Pyrimidinethione (9CI) is colorless or light yellow crystal.
2. Solubility: It is soluble in water, alcohols and ketones.

Use:
1. 4(1H)-Pyrimidinethione (9CI) is often used as an organic catalyst in organic synthesis, such as the catalytic generation of thiazolones.
2. It can also be used as a pharmaceutical intermediate, such as for the synthesis of certain anticancer drugs and heterocyclic compounds.
3. As a precursor of plant hormones in vivo, it can be used in the field of agriculture.

Method:
The preparation of 4(1H)-Pyrimidinethione (9CI) can be obtained by the reaction of 4-chloropyrimidine and sodium thiocyanate.

Safety Information:
1. 4(1H)-Pyrimidinethione (9CI) has certain toxicity, should avoid inhalation, intake or contact with skin.
2. In the operation, need to wear protective gloves, protective glasses and protective mask and other personal protective equipment, and maintain good ventilation conditions.
3. To be stored in a dry, ventilated place, away from the fire and oxidant.
4. Waste should be disposed of in accordance with local regulations.

Please note that the above introduction is only some basic properties and applications of 4(1H)-Pyrimidinethione (9CI), the specific situation needs to be further understood and studied according to the actual application scenarios and related materials.

Last Update：2024-04-09 15:17:52