4(5)-(Hydroxyethyl)imidazole - Names and Identifiers
4(5)-(Hydroxyethyl)imidazole - Physico-chemical Properties
Molecular Formula | C5H8N2O
|
Molar Mass | 112.13 |
Density | 1.228±0.06 g/cm3(Predicted) |
Melting Point | 82 °C |
Boling Point | 359.8±17.0 °C(Predicted) |
Flash Point | 171.38°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 14.11±0.10(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.568 |
4(5)-(Hydroxyethyl)imidazole - Introduction
2-[1(3)H-Imidazol]-4-yl ethanol is an organic compound with the chemical formula C6H8N2O. The following is a description of the properties, uses, preparation and safety information of the substance:
Nature:
-Appearance: 2-[1(3)H-Imidazol]-4-yl ethanol is a colorless to pale yellow liquid.
-Solubility: It is soluble in water and organic solvents such as ethanol, methanol and ether.
Use:
- 2-[1(3)H-Imidazol]-4-yl ethanol is an intermediate of many chemical syntheses.
-It is often used as a catalyst for pharmaceutical research, organic synthesis and catalytic reactions.
Preparation Method:
The preparation method of 2-[1(3)H-Imidazol]-4-yl ethanol can be carried out by the following steps:
1. First, 2-cyanoimidazole is hydrogenated with hydrogen in the presence of a catalyst.
2. The resulting 2-aminoimidazole is then reacted with a haloalkane to form the corresponding 2-substituted imidazole.
3. Finally, the 2-substituent imidazole and acetaldehyde are reacted to generate 2-[1(3)H-Imidazol]-4-yl ethanol through condensation reaction.
Safety Information:
- 2-[1(3)H-Imidazol]-4-yl ethanol has no obvious toxicity under normal use conditions.
-However, as a chemical, any individual who comes into contact with it should follow proper laboratory safety practices.
-It should be stored in a dry, well-ventilated place, away from combustibles and oxidants.
-During use, wear appropriate personal protective equipment, such as protective glasses and gloves.
Last Update:2024-04-09 21:01:54