4,4,4-trifluoro-2-methylbutanoate

4,4,4-trifluoro-2-methylbutanoate - Names and Identifiers

Name	Methyl 4,4,4-trifluorobutyrate
Synonyms	Methyl 4,4,4-trifluorobutyrate METHYL 4,4,4-TRIFLUOROBUTYRATE Methyl 4,4,4-trifluorobutanoate methyl 4,4,4-trifluorobutanoate 4,4,4-trifluoro-2-methylbutanoate 4,4,4-Trifluoro-butyric acid methyl ester Butanoic acid, 4,4,4-trifluoro-, Methyl ester
CAS	2365-82-4
EINECS	219-122-2
InChI	InChI=1/C5H7F3O2/c1-10-4(9)2-3-5(6,7)8/h2-3H2,1H3

4,4,4-trifluoro-2-methylbutanoate - Physico-chemical Properties

Molecular Formula	C5H7F3O2
Molar Mass	156.1
Density	1.192
Boling Point	113°C
Flash Point	-16℃
Vapor Presure	126mmHg at 25°C
Storage Condition	Room Temprature
Refractive Index	1.345

4,4,4-trifluoro-2-methylbutanoate - Risk and Safety

Risk Codes	10 - Flammable
Safety Description	16 - Keep away from sources of ignition.
UN IDs	3272
Hazard Note	Flammable
Hazard Class	IRRITANT, FLAMMABLE

4,4,4-trifluoro-2-methylbutanoate - Introduction

Methyl 4,4,4-trifluorobutyrate is an organic compound with the chemical formula CH3OC(O)CF3. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: colorless liquid
-Melting point:-40 ° C
-Boiling point: 108 ° C
-Density: 1.414g/cm³
-Solubility: Soluble in organic solvents, such as ethanol, acetone
-Stability: Stable at room temperature, but avoid high temperature, open flame or strong oxidant.

Use:
-chemical raw materials: can be used as organic synthesis reagents, catalysts and solvents.
-Pesticides/Insecticides: can be used as raw materials for pesticides in the agricultural field.
-Medicine: It is used in the synthesis of certain drugs.
-Surface treatment agent: can be used as solvent, surface treatment agent and additive.

Method:
Methyl 4,4,4-trifluorobutyrate can be obtained by the following preparation method:
-Esterification of dimethyl malonate with trifluoroacetic acid to give dimethyl 4,4, 4-trifluorobutyrate.
-Then, 4,4, 4-trifluorobutyric acid dimethyl ester and sodium chloride (NaCl) are used as a catalyst to undergo a transesterification reaction under acidic conditions to obtain Methyl 4,4,4-trifluorobutyrate.

Safety Information:
- Methyl 4,4,4-trifluorobutyrate exposure may cause irritation, avoid contact with eyes, skin and respiratory tract.
-Wear appropriate personal protective equipment such as gloves, safety glasses and a protective mask during use.
-should be stored in a cool, dry, well-ventilated place, away from fire and oxidizing agents.
-Observe relevant safety procedures and regulations during handling and storage. If inhaled or ingested, seek medical attention immediately.

Last Update：2024-04-09 02:00:44