4,4,5,5-tetraMethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane - Names and Identifiers
Name | 4,4,5,5-tetraMethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane
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Synonyms | 2-(1-PHENYLETHYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE 4,4,5,5-tetraMethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane
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CAS | 174090-36-9
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4,4,5,5-tetraMethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane - Physico-chemical Properties
Molecular Formula | C14H21BO2
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Molar Mass | 232.12634 |
Storage Condition | 2-8°C |
4,4,5,5-tetraMethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane - Upstream Downstream Industry
4,4,5,5-tetraMethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane - Introduction
4,4,5,5-tetramethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane, also known as 4,4,5,5-tetramethyl-2-(1-phenylethyl)-1,3, 2-dioxaboricane, an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Molecular formula: C15H23BO2
-Molecular weight: 250.16g/mol
-Solubility: Soluble in many organic solvents, such as ethers, alcohols and aromatic hydrocarbons.
Use:
4,4,5,5-tetramethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane is commonly used as a reagent or reaction intermediate in organic synthesis. Specific applications include:
-Participate in Suzuki coupling reactions for the synthesis of aromatic compounds.
-As an Organoboron reagent in organic synthesis, it participates in reduction reactions and functional group conversion of hydrocarbons.
-Participate in C- C bond formation reactions, such as Pd-catalyzed Heck reaction and Sonogashira Reaction.
Method:
4,4,5,5-tetramethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane can be prepared:
1. The reaction of phenyl ethyl ketone and 2,4-pentanedione in titanium palladium chloride catalysis generates the corresponding aryl borate ester.
2. The reaction of aryl borate ester with tetramethylborane under alkaline conditions to generate the target product.
Safety Information:
Although there are no detailed reports on 4,4, 5,5-tetrathyl-2-(1-phenylethyl)-1,3,2-dioxaborolane, appropriate laboratory safety measures should be taken for general organic compounds. These measures include wearing protective clothing, gloves and goggles, ensuring that the operation is carried out in a well-ventilated area and avoiding contact with skin and eyes. It should be stored in a dry, cool place, away from fire and oxidizing agents. Local laws and regulations shall be observed when using or disposing.
Last Update:2024-04-10 22:29:15