4,5-Dicyano-2-propyl-1H-imidazole
2-propyl-1H-imidazole-4,5-dicarbonitrile
CAS: 51802-42-7
Molecular Formula: C8H8N4
4,5-Dicyano-2-propyl-1H-imidazole - Names and Identifiers
| Name | 2-propyl-1H-imidazole-4,5-dicarbonitrile |
| Synonyms | Olmesartan Impurity 64 Olmesartan Medoxomil-17 Olmesartan Medoxomil Impurity 4 4,5-Dicyano-2-propyl-1H-imidazole 2-PropyliMidazole-4,5-dicarbonitrile 2-Propylimidazole-4,5-dicarbonitrile 2-propyl-1H-imidazole-4,5-dicarbonitrile 2-PROPYL-1H-IMIDAZOLE-4,5-DICARBONITRILE 1H-Imidazole-4,5-dicarbonitrile, 2-propyl- |
| CAS | 51802-42-7 |
| InChI | InChI=1/C8H8N4/c1-2-3-8-11-6(4-9)7(5-10)12-8/h2-3H2,1H3,(H,11,12) |
4,5-Dicyano-2-propyl-1H-imidazole - Physico-chemical Properties
| Molecular Formula | C8H8N4 |
| Molar Mass | 160.18 |
| Density | 1.21 |
| Melting Point | 141-143 |
| Boling Point | 485.1±30.0 °C(Predicted) |
| Flash Point | 152.5°C |
| Vapor Presure | 1.45E-09mmHg at 25°C |
| pKa | 5.57±0.10(Predicted) |
| Refractive Index | 1.543 |
4,5-Dicyano-2-propyl-1H-imidazole - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
4,5-Dicyano-2-propyl-1H-imidazole - Introduction
2-propyl-1H-imidazole-4,5-dicarbonitrile is an organic compound with the molecular formula C9H9N5, and its structure contains an imidazole ring and two cyano groups. Its nature is as follows:
1. Appearance: 2-propyl-1H-imidazole-4,5-dicarbonitrile is a colorless crystalline solid.
2. Solubility: Soluble in some organic solvents, such as alcohols, ketones and esters, and low solubility in water.
3. Melting Point: The melting point of 2-propyl-1H-imidazole-4,5-dicarbonitril is about 110-113°C.
4. Stability: The compound is relatively stable under conventional chemical reaction conditions.
The main use of 2-propyl-1H-imidazole-4,5-dicarbonitrile is as an intermediate in organic synthesis. It can be used in the synthesis of imidazole compounds, for example as an intermediate in the synthesis of aromatic compounds or as a ligand in the synthesis of metal complexes.
A common method for preparing 2-propyl-1H-imidazole-4,5-dicarbonitril is obtained by reacting 2-propylimidazole with hydrocyanic acid, followed by adding sodium cyanite or azobenzene peroxide for oxidation reaction, and finally obtaining the target product.
Regarding safety information, due to the lack of clear literature data, the safety information of this compound may be limited. Because it contains cyano groups, care should be taken to avoid inhalation or ingestion and to avoid prolonged contact with skin and eyes. During use, please follow appropriate laboratory procedures and safety measures, and learn more about them through the laboratory's safety data sheet.
1. Appearance: 2-propyl-1H-imidazole-4,5-dicarbonitrile is a colorless crystalline solid.
2. Solubility: Soluble in some organic solvents, such as alcohols, ketones and esters, and low solubility in water.
3. Melting Point: The melting point of 2-propyl-1H-imidazole-4,5-dicarbonitril is about 110-113°C.
4. Stability: The compound is relatively stable under conventional chemical reaction conditions.
The main use of 2-propyl-1H-imidazole-4,5-dicarbonitrile is as an intermediate in organic synthesis. It can be used in the synthesis of imidazole compounds, for example as an intermediate in the synthesis of aromatic compounds or as a ligand in the synthesis of metal complexes.
A common method for preparing 2-propyl-1H-imidazole-4,5-dicarbonitril is obtained by reacting 2-propylimidazole with hydrocyanic acid, followed by adding sodium cyanite or azobenzene peroxide for oxidation reaction, and finally obtaining the target product.
Regarding safety information, due to the lack of clear literature data, the safety information of this compound may be limited. Because it contains cyano groups, care should be taken to avoid inhalation or ingestion and to avoid prolonged contact with skin and eyes. During use, please follow appropriate laboratory procedures and safety measures, and learn more about them through the laboratory's safety data sheet.
Last Update：2024-04-10 22:29:15
