4,5-Dihydroxy-1,2-benzenedicarbonitrile

4,5-Dihydroxy-1,2-benzenedicarbonitrile - Names and Identifiers

Name	4,5-Dihydroxy-1,2-benzenedicarbonitrile
Synonyms	4,5-Dihydroxyphthalonitrile 4,5-Dihydroxy-1,2-Benzenedicar 4,5-dihydroxy, 2-benzenedicarbonitrile 4,5-Dihydroxy-1,2-benzenedicarbonitrile 4,5-dihydroxybenzene-1,2-dicarbonitrile 1,2-benzenedicarbonitrile, 4,5-dihydroxy- 1,2-BENZENEDICARBONITRILE, 4,5-DIHYDROXY-
CAS	300853-66-1
InChI	InChI=1/C8H4N2O2/c9-3-5-1-7(11)8(12)2-6(5)4-10/h1-2,11-12H

4,5-Dihydroxy-1,2-benzenedicarbonitrile - Physico-chemical Properties

Molecular Formula	C8H4N2O2
Molar Mass	160.13
Density	1.53±0.1 g/cm3(Predicted)
Boling Point	462.7±45.0 °C(Predicted)
Flash Point	233.619°C
Vapor Presure	0mmHg at 25°C
pKa	6.00±0.23(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.668

4,5-Dihydroxy-1,2-benzenedicarbonitrile - Introduction

4,5-dihydroxy-1, 2-benzenedicarbonitril (4,5-dihydroxy-1, 2-benzenedicarbonitril) is an organic compound with the chemical formula C8H4N2O2. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: 4,5-dihydroxy-1, 2-benzenedicarbonitril is a white solid.
-Solubility: Soluble in some polar organic solvents, such as alcohols and ketones, but insoluble in water.
-Melting point: Its melting point is about 230-235 ° C.

Use:
4,5-dihydroxy-1, 2-benzenedicarbonitril has certain applications in drug synthesis and organic synthesis:
-In the pharmaceutical field, it can be used as an intermediate for the synthesis of certain biologically active molecules.
-In the field of organic synthesis, it can be used as a starting material for the construction of carbon-nitrogen bonds, and through further chemical reactions, other organic compounds are generated.

Method:
The preparation method of 4,5-dihydroxy-1, 2-benzenedicarbonitril can be carried out by the following steps:
1.2-nitrobenzoic acid was prepared by reacting phthalic acid with nitrous acid.
2. 2-nitrobenzoic acid reacts with ammonia and alkali to generate 2-aminobenzoic acid.
3. 2-Aminobenzoic acid reacts with sodium cyanide to form 4,5-dihydroxy-1, 2-benzenedicarbonitril.

Safety Information:
-4,5-dihydroxy-1, 2-benzenedicarbonitril has low toxicity, but as an organic compound, it still needs to be handled carefully.
-Wear protective glasses and gloves during operation.
-Avoid direct contact with skin and inhalation of gas or dust.
-In storage and handling, should be placed in a closed container, away from combustibles and oxidants.

It should be noted that the above information is for reference only. Please conduct the necessary safety assessment before operation, and follow the correct laboratory operating specifications when conducting chemical experiments.

Last Update：2024-04-09 15:17:56