4-((4-Aminophenyl)sulfonyl)morpholine

4-((4-Aminophenyl)sulfonyl)morpholine - Names and Identifiers

Name	4-(morpholinosulfonyl)aniline
Synonyms	BRN 0226384 AKOS MSC-0718 Compound 82 208 4-(Morpholinosulfonyl) Morpholine, 4-sulfanilyl- 4-(Morpholinosulfonyl)aniline 4-(morpholinosulfonyl)aniline Morpholine, 4-sulfanilyl- (8CI) 4-Aminophenyl morpholino sulfone 4-(morpholin-4-ylsulfonyl)aniline p-Aminobenzene sulfonyl morpholine 4-(4-Morpholinylsulfonyl)-benzenamine 4-(Morpholine-4-Sulfonyl)-Phenylamine 4-(MORPHOLINE-4-SULFONYL)-PHENYLAMINE 4-((4-Aminophenyl)sulfonyl)morpholine Morpholine, 4-((4-aminophenyl)sulfonyl)- 4-27-00-00618 (Beilstein Handbook Reference)
CAS	21626-70-0
InChI	InChI=1/C10H14N2O3S/c11-9-1-3-10(4-2-9)16(13,14)12-5-7-15-8-6-12/h1-4H,5-8,11H2

4-((4-Aminophenyl)sulfonyl)morpholine - Physico-chemical Properties

Molecular Formula	C10H14N2O3S
Molar Mass	242.29
Density	1.360±0.06 g/cm3(Predicted)
Melting Point	216 °C
Boling Point	442.1±55.0 °C(Predicted)
Flash Point	221.1°C
Vapor Presure	5.18E-08mmHg at 25°C
pKa	2.49±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.604

4-((4-Aminophenyl)sulfonyl)morpholine - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S24/25 - Avoid contact with skin and eyes.
HS Code	29349990
Hazard Note	Harmful
Hazard Class	IRRITANT

4-((4-Aminophenyl)sulfonyl)morpholine - Introduction

4-(morpholinosulfonyl)aniline is an organic compound with the chemical formula C12H16N2O3S. It is a white crystalline solid, odorless, soluble in ethanol and dichloromethane.

4-(morpholinosulfonyl)aniline can be used as a synthetic intermediate of sulfonamide compounds. It can be used to prepare compounds such as pharmaceuticals, pesticides and dyes. It has important applications in organic synthesis.

A method for preparing 4-(morpholinosulfonyl)aniline is generally obtained by reacting 4-aminobenzenesulfonic acid with Morpholine. First, 4-aminobenzenesulfonic acid is dissolved in sodium hydroxide solution, and then morpholine is slowly added dropwise. Heat is generated during the reaction. After completion of the reaction, the precipitate was filtered, washed and dried to obtain 4-(morpholinosulfonyl)aniline.

Regarding safety information, 4-(morpholinosulfonyl)aniline is relatively stable at room temperature. But it can be irritating to the eyes, skin and respiratory tract. When handling the compound, wear appropriate protective equipment to avoid inhalation, contact with the skin, and entry into the eyes. Care should be taken to avoid contact with strong oxidants during use and storage. In case of accidental application or contact with skin, rinse immediately with clean water and seek medical attention.

Last Update：2024-04-09 20:02:46