4-(1-Aminomethyl)benzonitrile

4-(1-Aminomethyl)benzonitrile - Names and Identifiers

Name	4-(1-aminoethyl)-Benzonitrile
Synonyms	4-(1-aminoethyl)benzonitrile 4-(1-Aminomethyl)benzonitrile 4-(1-aminoethyl)-Benzonitrile Benzonitrile, 4-(1-aminoethyl)- 4-(1-AMinoethyl)-benzonitrile HCl
CAS	86225-78-7
InChI	InChI=1S/C9H10N2/c1-7(11)9-4-2-8(6-10)3-5-9/h2-5,7H,11H2,1H3

4-(1-Aminomethyl)benzonitrile - Physico-chemical Properties

Molecular Formula	C9H10N2
Molar Mass	146.19
Density	1.06±0.1 g/cm3(Predicted)
Boling Point	273.7±23.0 °C(Predicted)
pKa	8.42±0.10(Predicted)
Storage Condition	2-8°C

4-(1-Aminomethyl)benzonitrile - Introduction

4-(1-aminoethyl)-Benzonitrile is an organic compound with the chemical formula C9H10N2 · HCl. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 4-(1-aminoethyl)-Benzonitrile as white crystalline powder;
-Solubility: Soluble in water, alcohol and ether, slightly soluble in chloroform and benzene;
-Melting point: about 162-164 ℃.

Use:
4-(1-aminoethyl)-Benzonitrile is an important intermediate in the synthesis of drugs and organic synthesis, and has a wide range of applications:
-It can be used to prepare compounds with biological activity, such as pharmaceutical ingredients, dyes and auxiliaries, etc;
-It can also be used as a raw material for organic electroluminescent materials and optoelectronic devices.

Preparation Method:
4-(1-aminoethyl)-Benzonitrile can be synthesized by the following steps:
1. reacting benzonitrile with chloroethanol to generate 4-(chloroethoxy)-benzonitrile;
2. reacting 4-(chloroethoxy)-benzonitrile with ammonia to generate 4-(1-aminoethyl)-benzonitrile;
3.4-(1-aminoethyl)-benzonitrile is reacted with hydrochloric acid to generate 4-(1-aminoethyl)-Benzonitrile.

Safety Information:
- 4-(1-aminoethyl)-Benzonitrile should follow general laboratory safety procedures when using, storing and handling;
-It may be irritating to the eyes, skin and respiratory tract, contact and inhalation should be avoided;
-Wear appropriate personal protective equipment such as protective gloves, glasses and protective masks when used;
-In case of contact, rinse immediately with water or seek medical help.

Last Update：2024-04-09 15:18:00