4-(1H-imidazol-4-yl)pyridine - Names and Identifiers
4-(1H-imidazol-4-yl)pyridine - Physico-chemical Properties
Molecular Formula | C8H7N3
|
Molar Mass | 145.16 |
Melting Point | 195-196℃ (acetone hexane ) |
Storage Condition | 2-8°C |
4-(1H-imidazol-4-yl)pyridine - Introduction
Pyridine, 4-(1H-imidazol-4-yl)-is an organic compound with the chemical formula C9H8N2, which has an imidazole ring and a pyridine ring in the structure. The following is a description of its nature, use, formulation and safety information:
Nature:
Pyridine, 4-(1H-imidazol-4-yl)-is a white crystalline solid with a strong aromatic odor. It is poorly soluble and readily soluble in polar organic solvents such as ethanol and dimethylformamide. It is stable to air and light, but may decompose at high temperatures.
Use:
Pyridine, 4-(1H-imidazol-4-yl)-is often used as a catalyst and ligand in organic synthesis. It can be used for catalytic hydrogenation, reduction, oxidation and other processes of organic reactions. In addition, it can also be used as a ligand for metal complexes for the synthesis of catalysts and materials.
Preparation Method:
Generally, Pyridine, 4-(1H-imidazol-4-yl)-is prepared by a nucleophilic substitution reaction between pyridine and imidazole. In general, pyridine is first reacted with chloroacetic acid to form the corresponding ester intermediate. The imidazole is then reacted with the esterified compound to produce the desired product.
Safety Information:
Pyridine, the toxicity of 4-(1H-imidazol-4-yl)-is low, but it is still necessary to pay attention to safe operation. Rinse immediately with plenty of water when in contact with skin and eyes. Avoid inhaling its dust or gas, and pay attention to protective measures such as gloves and goggles when using it. At the same time, it should be stored in a dry, well-ventilated place, away from high temperature and fire sources.
Last Update:2024-04-10 22:29:15