4-(1H-pyrazol-1-yl)piperidine

4-(1H-pyrazol-1-yl)piperidine - Names and Identifiers

Name	4-(1H-pyrazol-1-yl)piperidine
Synonyms	LogP 4-(Pyrazol-1-yl)piperidine 4-(1H-pyrazol-1-yl)piperidine Piperidine,4-(1H-pyrazol-1-yl) 4-(1H-pyrazole-1-yl)piperidine Piperidine, 4-(1H-pyrazol-1-yl)- (9CI)
CAS	762240-09-5
InChI	InChI=1/C8H13N3/c1-4-10-11(7-1)8-2-5-9-6-3-8/h1,4,7-9H,2-3,5-6H2

4-(1H-pyrazol-1-yl)piperidine - Physico-chemical Properties

Molecular Formula	C8H13N3
Molar Mass	151.21
Density	1.21±0.1 g/cm3(Predicted)
Boling Point	272.5±33.0 °C(Predicted)
Flash Point	118.6°C
Vapor Presure	0.00607mmHg at 25°C
pKa	9.83±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.632

4-(1H-pyrazol-1-yl)piperidine - Introduction

4-(1H-pyrazol-1-yl)piperidine is an organic compound whose chemical formula is C10H16N2. It is an organic base with the appearance of white crystals or white to pale yellow crystalline powder.

4-(1H-pyrazol-1-yl)piperidine has a wide range of applications in medicinal chemistry and organic synthesis. It can be used as a ligand or catalyst in organic synthesis reactions, such as hydrogenation, reduction and carbonylation reactions. In addition, it can also be used in the preparation of other organic compounds, such as drugs, dyes and heterocyclic compounds.

There are several methods for synthesizing 4-(1H-pyrazol-1-yl)piperidine. The commonly used method is obtained by the reaction of pyrazole and piperidine, and one of the synthetic routes is to react pyrazole with piperidine hydrochloride, and under appropriate conditions, the target product can be obtained by adding a base to remove Salt.

Regarding safety information, the toxicity of 4-(1H-pyrazol-1-yl)piperidine is low. However, as an organic substance, it may have irritating effects on the skin, eyes and respiratory system. Therefore, appropriate personal protective measures, such as wearing gloves, glasses and respiratory protection equipment, are required during use and handling. During storage and handling, it should be stored in a sealed container and avoid contact with oxidants and ignition sources. When disposing of waste, it is necessary to comply with local environmental regulations and carry out correct disposal. In the use of the process, should strictly follow the chemical safety procedures.

Last Update：2024-04-09 20:48:19