4-(1h-indol-2-yl)phenylamine

4-(1h-indol-2-yl)phenylamine - Names and Identifiers

Name	4-(1H-indol-2-yl)aniline
Synonyms	4-(1H-Indol-2-yl)anilin 2-(4-aminophenyl)indole 2-(p-aminophenyl)indole 2-(p-aminophenyl)-indol 4-(1H-indol-2-yl)aniline 4-(1h-indol-2-yl)phenylamine BENZAMIDE,4-(1H-INDOL-2-YL)- 4-(1H-INDOL-2-YL)-PHENYLAMINE benzenamine, 4-(1H-indol-2-yl)-
CAS	21889-05-4
InChI	InChI=1/C14H12N2/c15-12-7-5-10(6-8-12)14-9-11-3-1-2-4-13(11)16-14/h1-9,16H,15H2

4-(1h-indol-2-yl)phenylamine - Physico-chemical Properties

Molecular Formula	C14H12N2
Molar Mass	208.26
Density	1.229±0.06 g/cm3(Predicted)
Melting Point	201-202 °C(Solv: ethanol (64-17-5))
Boling Point	441.2±20.0 °C(Predicted)
Flash Point	250.9°C
Vapor Presure	5.53E-08mmHg at 25°C
pKa	17.48±0.30(Predicted)
Storage Condition	2-8°C
Sensitive	Light Sensitive
Refractive Index	1.726

4-(1h-indol-2-yl)phenylamine - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
HS Code	29339900

4-(1h-indol-2-yl)phenylamine - Introduction

4-(lH-indol-2-yl) aniline is an organic compound with the chemical formula C14H12N2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 4-(1H-indol-2-yl) aniline is a uniform white crystalline powder.
-Solubility: It can be dissolved in some organic solvents, such as chloroform, dimethyl sulfoxide and dichloromethane, slightly soluble in benzene and alcohol.
-Melting point: Its melting point is about 100-102 ° C.
-Stability: The compound is relatively stable at room temperature.

Use:
- 4-(1H-indol-2-yl) aniline can be used as an intermediate in organic synthesis. It can be used in the synthesis of indole compounds and a variety of organic materials.
-It is also widely used in the field of medicine, for the synthesis of anti-cancer drugs, antiviral drugs and other drugs.

Method:
- 4-(1H-indol-2-yl) aniline can be prepared by nucleophilic aromatic substitution reaction between aniline and indole under reaction conditions.

Safety Information:
- 4-(1H-indol-2-yl) aniline has no reported major hazards under normal conditions of use.
-However, Good Laboratory Practices and safe operating procedures should be followed when handling this compound.
-It may cause irritation to the eyes, skin and respiratory tract, and direct contact should be avoided.
-Use with care to avoid inhalation, ingestion or skin contact, and wear appropriate personal protective equipment, such as laboratory gloves and protective glasses.
-In case of accidental contact, flush the affected area with plenty of water and seek medical attention if necessary.

Last Update：2024-04-09 20:45:29