4-(2-ISOPROPYL-IMIDAZOL-1-YL)-PHENYLAMINE
4-(2-Isopropyl-imidazol-1-yl)-phenylamine
CAS: 745737-06-8
Molecular Formula: C12H15N3
4-(2-ISOPROPYL-IMIDAZOL-1-YL)-PHENYLAMINE - Names and Identifiers
4-(2-ISOPROPYL-IMIDAZOL-1-YL)-PHENYLAMINE - Physico-chemical Properties
| Molecular Formula | C12H15N3 |
| Molar Mass | 201.27 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD07658298 |
4-(2-ISOPROPYL-IMIDAZOL-1-YL)-PHENYLAMINE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
4-(2-ISOPROPYL-IMIDAZOL-1-YL)-PHENYLAMINE - Introduction
4-(2-Isopropyl-imidazol-1-yl)-phenylamine is a commonly used organic compound with a variety of applications and properties.
Nature:
-Molecular formula: C13H18N2
-Molecular weight: 202.30g/mol
-Appearance: Colorless crystalline solid
-melting point: about 88-92 ℃
-Boiling point: about 365 ℃
-Density: about 1.15g/cm³
-Solubility: Slightly soluble in water, soluble in organic solvents (such as ethanol, ether and dichloromethane).
Use:
4-(2-Isopropyl-imidazol-1-yl)-phenylamine is an important intermediate compound, which is widely used in pharmaceutical synthesis and material science research. Specific applications include:
-Drug development: can be used as anticancer drugs, antiviral drugs and anti-inflammatory drugs raw materials.
-Organic synthesis: can be used as a starting material for the synthesis of natural products and organic compounds.
-Coordination chemistry: can be used for the synthesis of metal organic complexes.
Preparation Method:
4-(2-Isopropyl-imidazol-1-yl)-phenylamine has many preparation methods, but the commonly used synthetic routes include:
1.2-methyl acetone is reacted with thionamide to obtain 2-methyl propylene amine.
2.2-Methyl propylamine reacts with benzyl magnesium bromide to generate dialkyl benzylamine.
3. The dialkylbenzylamine is reacted with aldehyde for Knoevenagel condensation reaction to obtain 4-(2-methyl propenyl)-N,N-diethyl benzylamine.
4. Finally, 4-(2-methylpropenyl)-N,N-diethylbenzylamine is converted into 4-(2-Isopropyl-imidazol-1-yl)-phenylamine by acylation reaction.
Safety Information:
In the use, preparation and handling of 4-(2-Isopropyl-imidazol-1-yl)-phenylamine, the relevant safety procedures should be observed. These procedures include:
-Avoid contact with eyes, skin and clothing.
-Use in a well-ventilated place to avoid inhaling aerosols or dust.
-Use personal protective equipment such as lab gloves, goggles and lab coats.
-Store in a dry, cool, ventilated place away from combustibles and oxidants.
-Dispose of waste properly in strict compliance with local laws and regulations.
Nature:
-Molecular formula: C13H18N2
-Molecular weight: 202.30g/mol
-Appearance: Colorless crystalline solid
-melting point: about 88-92 ℃
-Boiling point: about 365 ℃
-Density: about 1.15g/cm³
-Solubility: Slightly soluble in water, soluble in organic solvents (such as ethanol, ether and dichloromethane).
Use:
4-(2-Isopropyl-imidazol-1-yl)-phenylamine is an important intermediate compound, which is widely used in pharmaceutical synthesis and material science research. Specific applications include:
-Drug development: can be used as anticancer drugs, antiviral drugs and anti-inflammatory drugs raw materials.
-Organic synthesis: can be used as a starting material for the synthesis of natural products and organic compounds.
-Coordination chemistry: can be used for the synthesis of metal organic complexes.
Preparation Method:
4-(2-Isopropyl-imidazol-1-yl)-phenylamine has many preparation methods, but the commonly used synthetic routes include:
1.2-methyl acetone is reacted with thionamide to obtain 2-methyl propylene amine.
2.2-Methyl propylamine reacts with benzyl magnesium bromide to generate dialkyl benzylamine.
3. The dialkylbenzylamine is reacted with aldehyde for Knoevenagel condensation reaction to obtain 4-(2-methyl propenyl)-N,N-diethyl benzylamine.
4. Finally, 4-(2-methylpropenyl)-N,N-diethylbenzylamine is converted into 4-(2-Isopropyl-imidazol-1-yl)-phenylamine by acylation reaction.
Safety Information:
In the use, preparation and handling of 4-(2-Isopropyl-imidazol-1-yl)-phenylamine, the relevant safety procedures should be observed. These procedures include:
-Avoid contact with eyes, skin and clothing.
-Use in a well-ventilated place to avoid inhaling aerosols or dust.
-Use personal protective equipment such as lab gloves, goggles and lab coats.
-Store in a dry, cool, ventilated place away from combustibles and oxidants.
-Dispose of waste properly in strict compliance with local laws and regulations.
Last Update：2024-04-09 21:00:56
